The event marked the promotion's third visit to Edmonton and first since
UFC 240 in July 2019. A flyweight bout between former two-time
UFC Flyweight Champion Brandon Moreno and
Amir Albazi headlined the event. The bout was initially scheduled for
UFC Fight Night: Magny vs. Prates, but was moved to this event shortly after. They were previously expected to meet at
UFC Fight Night: Moreno vs. Royval 2 earlier in the year but Albazi withdrew due to a neck injury. A women's flyweight bout between
Erin Blanchfield and former two-time
UFC Women's Strawweight Champion Rose Namajunas was originally scheduled to headline the event. However, in September, it was announced that the bout was shifted to the co-main event but remained five rounds. However, the promotion opted to split the pairing, with Lewis facing
Jhonata Diniz and Romanov facing
Rodrigo Nascimento instead. After the weigh-ins, Lewis was forced to withdraw from the fight due to non-weight cut related medical issues, so his bout against Diniz was scrapped. ==Results==