The effect of ultra-processed foods on health has mainly been investigated using
nutritional epidemiology and so far there has been no
randomized controlled trial to investigate the effect of these foods on any health outcome other than weight gain. These studies have shown an overall increased risk for diseaseincluding poor cardiometabolic and
mental health, and reduced life expectancyalthough studies separating different types of ultra-processed food have found adverse effects mainly for only some sub-groups such as
soft drinks and animal products, with some sub-groups such as cereals showing an inverse effect. Another study proposed that
food addiction may also be associated with consumption of ultra-processed foods. A 2026 study published by the
Milbank Quarterly journal compared the health impacts and addiction mechanisms of UPFs to cigarettes and called for similar regulations to that of
tobacco control. There is currently however no scientific consensus. UPF tend to be low in fibre and high in calories, salt,
added sugar and fat, which are all related to poor health outcomes when eaten excessively. Common examples include packaged snacks, soft drinks, ready meals, and processed meats. Ultra-processed diets promote overeating and weight gain, largely due to soft texture, high energy density and
hyperpalatable nutrient combinations that alter satiety and food-reward.
Obesity and weight gain Ultra-processed foods are designed to be highly palatable, typically combining high levels of sugar, fat, and salt to enhance flavor and texture. These foods often lack fiber and protein, which are essential for promoting the feeling of fullness and help regulate appetite.
Epidemiological data suggest that consumption of ultra-processed foods is associated with non-communicable diseases and
obesity. Observational studies have reported associations between higher consumption of ultra-processed foods and increased risk of certain cancers, particularly colorectal cancer and, to a lesser extent, breast cancer. However, evidence for other cancer types remains limited or inconsistent, and current findings do not establish a causal relationship. UPFs with certain additives, preservatives, and contaminants are also linked to an increase in cancer risk.
Diabetes A 2023 meta-analysis of 415,554 participants found that each 10% increase in ultra-processed food consumption was associated with a 12% higher risk for
type 2 diabetes. Some specific types of ultra-processed foods that have been associated with higher risk of type 2 diabetes include refined breads, sauces, spreads, condiments, artificially and sugar-sweetened beverages, animal-based products, and ready-to-eat mixed dishes. The high content of added sugars in many ultra-processed foods can lead to obesity, inflammation, and high blood pressure, all of which are risk factors for heart and cardiovascular disease. Ultra-processed foods often contain excessive amounts of sodium, which if consumed too often can lead to high blood pressure, a major risk factor for heart disease. A 2024 meta-analysis found that participants with the highest consumption of UPF had a 17% increased risk of cardiovascular disease compared to those with the lowest consumption. Health organizations worldwide, such as the World Health Organization and the
American Heart Association, recommend reducing the intake of ultra-processed foods to lower the risk of heart disease, advocating for diets rich in fruits, vegetables, whole grains, and lean proteins to promote heart health and prevent cardiovascular disease.
Association with all-cause mortality A 2025 meta-analysis found that participants with the highest consumption of UPF had a 15% increased risk of
all-cause mortality compared to those with the lowest consumption, also observing a 10% higher mortality risk with each 10% increment in UPF consumption. == Economics ==