Uncomfortable science, as identified by statistician John Tukey, comprises situations in which there is a need to draw an inference from a limited sample of data, where further samples influenced by the same cause system will not be available. More specifically, it involves the analysis of a finite natural phenomenon for which it is difficult to overcome the problem of using a common sample of data for both exploratory data analysis and confirmatory data analysis. This leads to the danger of systematic bias through testing hypotheses suggested by the data.