Early history In 1819,
Cincinnati College and the Medical College of Ohio were founded in Cincinnati. Local benefactor
Daniel Drake founded and funded the Medical College of Ohio. William Lytle of the
Lytle family donated the land, funded the Cincinnati College and Law College, and served as its first president. The college survived only six years before financial difficulties forced it to close. In 1835, Daniel Drake reestablished the institution, which eventually joined with the
Cincinnati Law School. In 1858, Charles McMicken died of pneumonia and in his will he allocated most of his estate to the
City of Cincinnati to found a university. The University of Cincinnati was chartered by the Ohio legislature in 1870 after delays by livestock and
veal lobbyists angered by the
liberal arts-centered curriculum and lack of agricultural and manufacturing emphasis . The university's board of rectors changed the institution's name to the University of Cincinnati.
Expansion and 20th century By 1893, the university expanded beyond its primary location on Clifton Avenue and relocated to its present location in the
Heights neighborhood. As the university expanded, the rectors merged the institution with Cincinnati Law School, establishing the
University of Cincinnati College of Law. In 1896, the Ohio Medical College joined Miami Medical College to form the Ohio-Miami Medical Department of the University of Cincinnati in 1909. As political movements for
temperance and
suffrage grew, the university established Teacher's College in 1905 and a Graduate School in the College of Arts and Sciences in 1906. The Queen City College of Pharmacy, acquired from
Wilmington College (Ohio), became the present James L. Winkle College of Pharmacy. In 1962, the
Cincinnati College-Conservatory of Music was acquired by the university. The Ohio legislature in
Columbus declared the university a "municipally-sponsored, state-affiliated" institution in 1968. During this time, the University of Cincinnati was the second oldest and second-largest municipal university in the United States. In 1971, the university became one of the first institutions in the United States to offer a
women's studies course, which was taught by
Monika Triest and Sylvia Tucker.
Modern history By an act of the
Ohio Legislature, the University of Cincinnati became a state institution in 1977. Over this time, the university invested nearly $2 billion in campus construction, renovation, and expansion ranging from the student union to a new recreation center to the medical school. It included renovation and construction of multiple buildings, a campus forest, and a university promenade. The plan also includes the
Sigma Sigma Commons, which was completed in 1998 as a part of the organization's centennial. Upon her inauguration in 2005, President
Nancy L. Zimpher developed the UC21 plan, designed to redefine Cincinnati as a leading urban research university. In addition, it includes putting liberal arts education at the center, increasing research funding, and expanding involvement in the city. In 2009,
Gregory H. Williams was named the 27th president of the University of Cincinnati. His presidency expanded the accreditation and property of the institution to regions throughout Ohio to compete with private and specialized state institutions, such as
Ohio State University. His administration focused on maintaining the integrity and holdings of the university. He focused on the academic master plan for the university, placing the academic programs of UC at the core of the strategic plan. The university invested in scholarships, funding for study abroad experiences, the university's advising program as it worked to reaffirm its history and academy for the future. Neville Pinto is the current and 30th president of the university. In the wake of the
George Floyd protests in 2020, a list of demands related to racial equity at the University of Cincinnati were sent to administrators by the Black Round Table and the UC Student Government, which included hiring more Black faculty, making the UC Police Department budget public, making
Election Day and
Juneteenth university holidays, and removing Charles McMicken's name across campus, as McMicken was a slave owner. Some of the demands had been made by the Irate 8 group in 2015 following the
killing of Samuel DuBose by a UC Police Department officer. In 2022, the university removed McMicken's name from campus. In 2025, under government mandate, the school announced that it would not strip away its
diversity, equity, and inclusion programs, however within a week the university replaced certain signs on the men's and women's bathrooms with ones that said "biological men" and "biological women", and announced they would preemptively comply with Ohio Senate bill 1 and executive orders from the
Trump administration. The signage was quickly changed back after backlash and multiple campus-wide protests. The University has since committed to preserving DEI initiatives. Despite these commitments, on June 24, 2025 the University announced that they would be closing down their LGBTQ Center, Women's Center, African American Cultural and Resource Center, as well as Ethnic Programs and Services. ==Campuses==