In 2015, Mukherjee won Miss Beauty of
Kolkata. Mukherjee began her film career in 2015 with
Raj Chakraborty's movie
Parbona Ami Chartey Tokey. In 2016, she appeared in
Kelor Kirti, a romantic comedy directed by
Raja Chanda. In
Kelor Kirti, she plays a wealthy young woman, Anuskha, who falls in love with a journalist. In 2017, she was cast in
Jio Pagla directed by
Ravi Kinnagi. In 2019 she was signed as the cover for FFACE Fashion Calendar. In the subsequent years, she acted in a number of romantic comedy films including
Hoichoi Unlimited (2018) directed by
Aniket Chattopadhyay,
Jamai Badal (2019) directed by Ravi Kinagi and
Baccha Shoshur (2019). She has collaborated with her fellow-actor
Bonny Sengupta multiple times for playing the lead pair in their films. In 2022, she was cast in the drama thriller
Antarjaal and adventure comedy
Hirokgorer Hire. In the same year, she worked in the
Avijit Sen directorial
Projapoti, which emerged as the highest grossing film that year. In 2023, she made her OTT debut with the
Zee5 Originals series
Abar Proloy directed by Raj Chakraborty. In 2024, Mukherjee made her
Dhallywood debut with
Dark World. In the following years, she received widespread critical acclaim and commercial success with
Bohurupi (2024) and
Killbill Society (2025).
Bohurupi eventually emerged as the
fourth highest grossing Indian Bengali film of all time. Her performance in
Bohurupi earned her a
Anandalok Puraskar for the
Best Actress and a nomination for the
Best Actress at the
8th Filmfare Awards Bangla. == Political career ==