cells adhered to bladder epithelial cell
Pathogenic E. coli from the gut is the cause of 75% of uncomplicated UTIs, and 65% of complicated UTIs. Rarely they may be due to
viral or
fungal infections. Healthcare-associated urinary tract infections (mostly related to
urinary catheterization) involve a much broader range of pathogens including:
Klebsiella pneumoniae,
Proteus mirabilis,
Pseudomonas aeruginosa and
Enterococcus faecalis. These species can form
biofilms and colonise catheters. These infections are usually classified as a
urethritis rather than urinary tract infection.
Intercourse In young sexually active women, sexual activity is the cause of 75–90% of bladder infections, with the risk of infection related to the frequency of sex. Condom use without spermicide or use of
birth control pills does not increase the risk of uncomplicated urinary tract infection.
Anal intercourse may increase the risk of UTI in men and in women if followed by vaginal sex. Although sex is a risk factor, UTIs are not classified as
sexually transmitted infections (STIs).
Sex Women are more prone to UTIs than men because, in females, the
urethra is much shorter and closer to the
anus. As a woman's estrogen levels decrease with
menopause, her risk of urinary tract infections increases due to the loss of protective
vaginal flora. Chronic prostatitis in the forms of
chronic prostatitis/chronic pelvic pain syndrome and
chronic bacterial prostatitis (not acute bacterial prostatitis or
asymptomatic inflammatory prostatitis) may cause recurrent urinary tract infections in males.