On 4 April 2006,
Roosevelt and the Dutch frigate attempted to intercept a hijacked South Korean
trawler off the coast of Somalia, but the ships were forced to disengage in the pursuit because the
pirates threatened the trawler's crew with firearms. The hijacked trawler escaped into Somali territorial waters. On 16 February 2007,
Roosevelt was awarded the 2006
Battle Efficiency "E" award. On 28 October 2011,
Roosevelt completed her seven-month deployment to the
U.S. Fifth Fleet and
Sixth Fleet areas of responsibility. During this overseas deployment, she was underway at sea for 205 days out of total of 213 days away from her homeport of
Naval Station Mayport. During the 205 days at sea, she logged one period of 113 consecutive days underway, travelling over . She made only three ports of call during her 2011 deployment, to
Rota, Spain; the island of
Mahe in the
Seychelles; and
Port Louis, the capital of
Mauritius. On 16 March 2014,
Navy SEALs operating from
Roosevelt took possession of the rogue oil tanker south of
Cyprus with the intent to deliver the vessel to Libyan authorities. From June to October 2017,
Roosevelt underwent a maintenance and modernization availability, called a Depot Modernization Period (DMP), at BAE Systems Jacksonville Repair Shipyard in
Jacksonville, Florida. During the DMP, the ship had several of her systems updated, as well as significant regular maintenance, and a reconfigured and redesigned galley. On 19 May 2019,
Roosevelt concluded her participation in the
NATO military exercise Formidable Shield 2019 in which she was one of the first
Aegis Combat System Baseline 9 ships to demonstrate the integrated air and missile defense (IAMD) capability. On 21 March 2020,
Roosevelt left her home port of Naval Station Mayport to shift her home port to
Naval Station Rota in Spain. She arrived on 16 May 2020 to replace . Her aft
Phalanx CIWS was replaced with a
SeaRAM CIWS. In May 2020,
Roosevelt operated in the
Barents Sea with , , , , and in the first U.S. exercise in the
Arctic waters since the mid-1990s. On 21 October,
Roosevelt completed her first Forward-Deployed Naval Forces-Europe (FDNF-E) patrol in the 6th Fleet (C6F) area of operations conducting naval operations in the Arctic, Mediterranean Sea, and Black Sea in support of U.S. national security interests in Europe and Africa. On 29 March 2021,
Roosevelt began her second FDNF-E patrol in the C6F area of operations.
Roosevelt, along with
Arleigh Burke, the , and a
P-8A from Patrol Squadron (VP) 46, conducted anti-submarine warfare (ASW) exercise Black Toro in the north Atlantic Ocean from 2–7 April 2021. In mid 2021, while in port at Rota,
Roosevelt was used to film the third season finale of the
Amazon Prime Video series
Jack Ryan, with many of the crew used as on-screen extras. On 11 December,
Roosevelt began her third FDNF-E patrol in the C6F area of operations. On 8 October 2023, the day after the
October 7 attacks, the U.S. Secretary of Defense,
Lloyd Austin, directed the
carrier strike group to the Eastern Mediterranean in response. Along with the aircraft carrier, the group also included the cruiser , and the destroyers ,
Carney,
Roosevelt, and . On 20 January 2026, during rising tensions between the United States and the Islamic Republic of Iran, it was reported to have returned to the Eastern Mediterranean as part of a US naval buildup around Iran. ==Coat of arms==