His thesis work led him to five further publications on "Ecological Succession," which were published in the
Biological Bulletin in 1911 and 1912. By 1913 he published one of his great works on ecology,
Animal Communities in Temperate America. He took a position for the
University of Illinois, where he ended up spending most of his career, in 1914 as an assistant and associate professor of zoology. From then he helped organize the
Ecological Society of America (ESA), and became its first president in 1916. He edited and helped compile ''Naturalist's Guide to the Americas
, a 761-page volume published in 1926 that served as an inventory of preserved natural areas and areas in need of protection, for the ESA. This helped him with his later work, The Ecology of North America'' (1963). By 1927 Shelford was made a full professor in his position at the University of Illinois. He also was interested in experimental research in both the field and the laboratory. In 1929 he had published
Laboratory and Field Ecology, which served as a method book for research in animal ecology. Shelford was known to travel into the field every summer to conduct research. He initiated the "century-cycle" project in 1933 at the University of Illinois' William Trelease Woods, which was used to study the relation between vertebrate and invertebrate populations with environmental factors. The first fifteen years of data collected from this project was published in 1951 in
Ecological Monographs. Shelford was the biologist in charge for the Illinois Natural History Survey at their research laboratories from 1914 to 1929. He had also been director of marine ecology at the
Puget Sound Biological Station during alternate summers from 1914 to 1930. Some of his work from this time was published in 1935 in
Ecological Monographs. ==Later life and work==