Main •
Josh Blaylock as Brian Doheny (commonly referred to as BrianD), an
FPS player and the main
protagonist of the series. •
Johanna Braddy as Jennifer Matthews (commonly referred to as Jenny Matrix), sophomore Junior Varsity team captain. • Ellary Porterfield as Kimberly Swan (commonly referred to as Ki Swan), a
video game developer and fighting game specialist who goes to the school to learn more about players. •
Jimmy Wong as Theodore Wong (commonly referred to as Ted), Brian's best friend, Ki's boyfriend, and the son of
Rhythm Game teacher Freddie Wong. • Brian Firenzi as Lawrence Pemberton (commonly referred to as The Law), a popular gamer. •
Cynthia Watros as Mary Matrix (seasons 2–3), coach for the
FPS Varsity team and Jenny's mother. •
Nathan Kress as New Law (season 3), who comes into play after The Law is kicked off of Napalm Energy's High School FPS team and is given The Law's I.P. and title.
Supporting •
Chase Williamson as Shane Barnstormer / Shane Pizza (Seasons 2 & 3), the head R.A. and eventual class president. • Bryan Forrest as Ashley Barnstormer (Seasons 2 & 3), Shane's
fraternal twin brother. • Joey Scoma as Randall Merryweather (goes under the alias Jumpin' Jax), a dim-witted FPS team member. • Benji Dolly as Games Dean, an FPS team member with a suave personality. • Nicole Wyland as Moriarty, an FPS team member. • Rocky Collins as the Drift King (commonly referred to as D.K.), a senior student and the captain/monarch of the Drift Racing team. • Joel Dauten as Scott Slanders, co-host of
PwnZwn. • Clinton Jones as ShotBot, robot co-host of
PwnZwn. :* Will Campos as the voice of ShotBot • Nat'han as the Tutor of NukeInc •
Zachary Levi as Ace (Season 1), teacher of FPS 101. •
Harley Morenstein as Dean Ernie Calhoun, a former VGHS student who values the heart of the game itself. • Brennan Murray as Wendell (Seasons 2 & 3) (gamertag TacoBoy14), a dorky student and also close friend of Ki. •
Freddie Wong as a fictionalized version of himself and an ex-world famous rhythm game player now working at Video Game High School. He is also Ted's father. • John Ennis as Kenneth Swan, Ki's father
Guests and cameos • Matthew Arnold as Zoostcaster •
Cliff Bleszinski as TheJackrabbit • Will Campos as Buddy Phelps •
Wesley Chan as K-Pop •
Chris Hardwick as Newsanchor •
Tony Hawk as Tony Hawk •
John Hennigan as Crazy Napalm Suit • Clinton Jones as Clint Lockwood •
Stan Lee as Stan L33t • Michael Rousselet as Alliterator ==Production and release==