Early years After his retirement as a player, he started a coaching career in Veneto for a number of amateur teams. In 2017, he joined
Union ArzignanoChiampo, which won him interest from
Serie C club
Trapani who hired him for the 2018–19 season. Under his guidance, Trapani concluded the 2018–19 season in second place behind champions
Juve Stabia, and then successfully contested the playoff phase, winning promotion to Serie B after defeating
Piacenza 2–0 on aggregate.
Spezia Following his successful season with Trapani, Italiano was subsequently hired by ambitious Serie B club
Spezia as the club's new head coach for the
2019–20 season. In his first season in charge, Italiano immediately achieved promotion with Spezia to
Serie A for the first time in the club's history after edging
Frosinone in the promotion play-offs. He successively guided Spezia in their
2020–21 Serie A campaign, succeeding in keeping the small Ligurian club in the top flight in his debut season in the Italian top division.
Fiorentina Italiano's successes with Spezia won him the interest of
Fiorentina, who ultimately signed him as their new head coach on a two-year deal. In his first season in charge, Italiano led Fiorentina to win a spot for the
2022–23 UEFA Europa Conference League by finishing 7th in
Serie A, thus marking a return into European football for the
Viola after several years. Despite interest from other clubs, Italiano was confirmed as Fiorentina manager for two more seasons. Italiano then led Fiorentina to the
2023 UEFA Europa Conference League Final the following season, the club's first European final since
1990. Their memorable campaign ended with a narrow 2–1 defeat to Premier League side
West Ham United in the final minute of regulation time. Fiorentina finished 8th in the
2022–23 season, in what seemed as though Fiorentina have missed out on European Competition but surprisingly qualified for the
2023–24 UEFA Europa Conference League due to seventh placed team, rivals
Juventus, being banned from Conference League and Europe altogether, so Fiorentina replaced Juventus as Italy's representative for the Conference League. Fiorentina also reached the
2023 Coppa Italia final, suffering a 2–1 defeat to
Inter Milan. He never started the same starting eleven in consecutive games during a 141-match run that ended on 2 March 2024, when he finally selected the same starting line-up against both
Lazio at home and
Torino away in the league. Italiano made even more history with Fiorentina as they qualified for the
2024 UEFA Europa Conference League Final, eliminating
Club Brugge 4–3 on aggregate in the semi-finals of the competition; Italiano became the first manager of Fiorentina to reach back to back European finals and the first to reach back to back Conference League finals. However, on 29 May, Fiorentina lost out to
Olympiacos 1–0, conceding late in the second half of
extra-time, their second consecutive final defeat in the competition. Following the final match of the Serie A season on 2 June, in which Fiorentina managed a 3–2 away win over
Atalanta, finishing in eighth place with 60 points and qualifying for the
Conference League for the third consecutive season, Italiano confirmed that he would be leaving the club in the summer.
Bologna On 5 June 2024, Italiano was officially appointed as the head coach of Serie A side
Bologna, signing a two-year contract with the club. On 14 May 2025, he led the club to a 1–0 victory over
Milan in the
Coppa Italia final, clinching their first title in the competition in 51 years. ==Style of management==