Horridge was born in
Sheffield, England, to George William Horridge (1897–1981) and Olive (1899–1995), daughter of Albert Stray, who owned a chain of sweetshops. The Horridge family had operated a business in Sheffield- William Horridge and Company, "Stag, Buck, Horn, Wood and Buffalo Handles, and Scale Cutters"- since 1750, producing amongst other things ivory scales for piano keys, combs, and knife handles. His paternal grandfather was the last to be involved with the company, which was sold in 1921 for £15,000 ("when you could buy a house for £100"); after
World War I, Horridge's father started a motorbike repair and sale business in his back yard, which expanded until he and a business partner were substantial motorcycle agents with a showroom and repair shops. He attended
King Edward VII School. He obtained a scholarship to
St John's College, Cambridge in 1946. He earned a PhD from the
University of Cambridge and was appointed to a Fellowship in Chemistry at St. John's in 1953. From 1960 till 1969, he was Director of the
Gatty Marine Laboratory at the
University of St Andrews. From 1969 till 1993, he was a professor at the Research School of Biological Sciences at the
Australian National University, and subsequently emeritus Professor. He lived in
Yarralumla, Canberra. In retirement he produced a number of books and articles on bee vision. In 1965, together with
Ted Bullock, he published the two-volume “bible of invertebrate neurobiology”:
Structure and Function in the Nervous System of Invertebrates. He received the Zoological Society of London Scientific Medal in 1968 for his work on the anatomy and physiology of nervous systems of invertebrates. He was elected a Fellow of the Royal Society in 1969 and to the Australian Academy of Science in 1971. In 2001 he was awarded a
Centenary Medal "for service to Australian society in the biological sciences". In 1975, he served for three months as the Chief Scientist aboard the US Research Ship Alpha Helix in the Moluccas, working mainly on the eyes of deep-sea animals. On this trip his interest in Indonesian sailboats developed. He wrote two books and numerous articles on Indonesian canoes and sailing craft. In 2019, a very large virus,
Megaklothovirus horridgei was named after him. ==Personal life==