The game begins with Wario and his friends at his company WarioWare Inc. (which includes Lulu, who previously appeared in
WarioWare: Gold) when Wario finishes the game unit they have been developing. When he tries to start it, the console does not turn on, much to Wario and his friends' confusion. Annoyed, Wario tosses the console in the air and he, along with his friends, get sucked inside the game, is turned into virtual versions of themselves, and enter the game. When they wake up, they discover that their game has been invaded by "Game
Bugs", which cause corruption and
glitches within the game's levels. Wario and his friends have to defeat these bugs to clean the game and return to the real world. Eventually, the group defeat the game's final bug, the Wario Bug, a corrupted and possessed version of Wario. They then leave the game bugs alone after Wario gives the bugs a home in the final level. "The Supreme Developer", a god-like figure with Wario's nose and mustache, appears to them after that and tells them that he brought Wario and his friends into the game to clear it of the game bugs, which Wario inadvertently caused due to his poor programming skills. He then tells the group that they are free to go. Back outside, everyone learns of Wario's involvement in developing the game bugs and angrily chase him down, but he notices that three of WarioWare's members (Red, Master Mantis and Lulu) are still stuck in the game, and the group goes back into the game to find them. Upon re-entering the game world, the Supreme Developer tells the group that their friends have been captured, although it was done by a mysterious figure and not the Game Bugs. They then progress through a series of skyscrapers that their friends are trapped within, all three of which have treasure inside of them. When all three pieces of treasure have eventually been collected, the group finds a note that dares them to combine the treasure. Dr. Crygor calls Penny (the only character who is not at WarioWare Inc.) to help after she invents the Jet Tank One in her lab. After she enters the game, they merge the treasures which turn into a watering can that they use to grow a giant beanstalk, but it vanishes afterward, to Wario's distress. They climb the beanstalk and defeat the final boss, who turns out to be Pyoro, the main character of a fictional game franchise within Wario's world, who took up residence in Wario's game too because he wanted to have fun. After his defeat, Wario is disappointed that Pyoro has no more treasure. == Reception ==