The Baltimore and Ohio Railroad was chartered in 1827 and grew to be one of the largest passenger railways in the United States, often by acquiring other, smaller railroads. B&O trains began operating between Chicago and Wheeling in 1880. From 1912 until 1956 the B&O provided overnight
sleeping car service between Chicago's Grand Central Station and Wheeling, West Virginia, on the
Wheeling Night Express, Train No. 46. The reverse route, Train No. 45, was served by the
Chicago Night Express. In 1928, the routes were consolidated with Train Nos. 15/16 from
Willard, Ohio, to Chicago. During
World War II, the
West Virginia Night Express was consolidated with Train No. 9, the
Pittsburgh-Chicago Express on the western end of the run from the junction at Willard, Ohio, to Chicago. In 1946, the
West Virginia Night Express resumed independent operation from Willard to Chicago. ==Decline and end of the train==