At age 18, Dubois moved to
Boston,
Massachusetts, to become the bookkeeper in the wholesale footwear business of his uncle, Wales Tucker. A year or two later, Dubois became a partner in the Boston wholesale footwear firm of James Tucker & Co., where he remained until 1864. Dubois was in ill health from overwork when he left Boston. After two years recuperating in Randolph, he moved to
New York City to become a partner in a new shoe and boot wholesaler, Dubois, Magovern & Co. He remained with this firm until 1872, when he returned to Randolph. ==Later career==