Holmes was born on 5 April 1689 in the parish of St Swithin, in the
City of London, the son of Thomas and Margaret Holmes of London, England. He began his education at
Merchant Taylors' School, London, on 12 September 1701 and went up to
St John's College, Oxford, on 11 June 1707,
matriculating on 2 July. In 1710, he became a
Fellow and graduated with a Bachelor of Arts degree on 16 May 1711, and was awarded the
Master of Arts degree on 9 April 1715. In 1721 Holmes was appointed as a
proctor of the University. He took the
Bachelor of Divinity degree on 13 April 1722 and the Doctorate of Divinity on 5 March 1725. Holmes held two college livings; between 1725 and 1726 that of
North Leigh, near
Oxford, and of
Henbury, Gloucestershire from 1726 to 1728. He was elected
President of St John's College on 3 June 1728. Holmes became the Rector of
Boxwell, Gloucestershire, on 24 September and was given the college living of Hanborough, a few miles north of
Long Hanborough, Oxfordshire, and between 1731 and 1737, he was proctor for the clergy of the
diocese of Oxford in
convocation. Holmes was
Vice-Chancellor of Oxford University between 1732 and 1735, At another time, Holmes refused a company of players from visiting Oxford. He was from 1728 to 1748 the
President of St John's College, Oxford. He was nominated by
George II to the deanery of
Exeter Cathedral on 4 June 1742. Holmes was buried in the college chapel, and on the instruction of his wife, Sarah, a monument to him was erected in the college chapel. On his death on 4 April 1748, Holmes left an estate of two farms and £200 a year to St John's College. ==Works==