Salter began his ministry in Jackson County, preaching in the Maquoketa area. In 1846 he became the second pastor of First Congregational Church in
Burlington, Iowa, and remained senior minister of this congregation for more than 60 years until his death in 1910. According to Jordan, "Salter played a dominant role in transforming the slovenly community, where filth filled the alleys, pigs wallowed in streets and cows grazed on the public square, into a prosperous and cultivated 20th-century Burlington." He was instrumental in establishing a public library and getting a library building built. He served as president of the school board. He was a trustee of the State University of Iowa (now the
University of Iowa), which awarded him an honorary doctorate. Prior to the Civil War, Salter not only allied himself with anti-slavery societies, but also operated an
Underground Railroad station to aid slaves fleeing to freedom. Runaways found sanctuary at his South Hill home and in a hidden room beneath his church. During the war, Salter visited Union troops as far south as Atlanta.
Social Gospel theologian
George Herron served briefly with Salter as associate minister in 1892 and 1893, before taking a position as professor of Applied Christianity at
Grinnell College. In 1876 he compiled and had published a compilation of the letters and speeches of
James W. Grimes, who served Iowa in the U.S.Senate and voted against convicting
President Andrew Johnson. ==Personal life==