The highway starts at its intersection with
WIS 33 and Division Street in
Stoddard and runs east along Coon Creek. After a
running concurrently with County Trunk Highway K (CTH-K), the highway goes through
Chaseburg and continues northeast. The highway runs along a short concurrency with
US Highway 14 (US 14) and
US 61. This short concurrency is a
wrong-way concurrency because WIS 162 and US 61 are signed in opposing directions throughout its length. Just west of
Coon Valley, the wrong-way concurrency ends as the highway runs north from it. After , the highway runs concurrently with
WIS 33, which ends at
Middle Ridge. After its intersection with CTH-JB, the highway runs along Dutch Creek. It intersects
Interstate 90 (I-90) before entering
Bangor. After a short concurrency with CTH-B, the highway runs north from Bangor. It runs concurrently with
WIS 16 before following Burns Creek. From the creek's end, the highway continues north until it terminates at
WIS 71 in
Four Corners. File:WIS162WestTerminusStoddardWIS35.jpg|Southwestern terminus File:Wisconsin Highway 162.jpg|WIS 162 near Bangor and I-90 File:FourCornersMonroeCountyWisconsinWIS71WIS162NorthernTerminus.jpg|Northern terminus ==Major intersections==