Starting at US 10 (exit 267) interchange, WIS 96 and WIS 110 begin to travel northward from CTH-II as a four-lane divided road. Shortly after that, WIS 96 turns east as a two-lane undivided road while WIS 110 turns west. Going east, WIS 96 meets
Readfield, US 45 at a roundabout,
Dale, and
Medina. Then, it meets WIS 76 just northwest of the
Appleton International Airport. Then, it meets I-41/US 41 at a diamond interchange. In Appleton, it then meets WIS 47. Just at the eastern city limit, it then passes under WIS 441 north of the Fox River. At this point, WIS 96 parallels the Fox River. The route then travels through
Little Chute,
Kaukauna, and
Wrightstown. Past Wrightstown, the route no longer parallels the Fox River. In Greenleaf, the route intersects with WIS 32. Between
Lark and
Shirley, WIS 96 travels northward. Then, it travels eastward to
Denmark. At the village limit of Denmark, WIS 96 ends at I-43 at a diamond interchange. ==Major intersections==