•
Cel Spellman as Drew Ferran, the titular character and main protagonist of the series. A young teenager who discovers he is not only the last werewolf, but the son and heir of the deposed wolf king Wergar. Honorable and courageous, Drew wants to protect his friends from their enemies. • Louis Landau as Trent Ferran, Tilly and Mack's son and Drew's adoptive brother •
David Yip as: • Hamwell (Season 1), a farmer from the town of Motley • Baron Huth, the boarlord of Redmire and father of Hector and Vincent •
Kim Adis as Erin (Season 1), Hamwell's daughter and Drew's childhood friend •
Peter Serafinowicz as: • Mack Ferran (Season 1), Drew's adoptive father • Duke Manfred, the staglord of Stormdale and a longtime ally of Bergan • Count Kesslar (Season 2), a goatlord and Ewan's cousin, whom he usurped and took control of Haggard •
Kate Fleetwood as: • Tilly Ferran (Season 1), Drew's adoptive mother • Duchess Rainier (Season 1), Bergan's wife and the mother of Broghan and Whitley • Queen Amelie, the mother of Drew and Lucas and the queen of Lyssia. Following the death of her first husband, King Wergar, she sent Drew away as an infant for safety and was forced to marry King Leopold. •
Rob Rackstraw as: • Lord Vanmorten, a ratlord who serves King Leopold as one of his chief enforcers • Lord Vankaskan, a ratlord and Vanmorten's twin brother. He is a magister who is capable of casting and manipulating dark magic. • Nina Barker Francis as Lady Whitley, a werebear, Bergan's daughter, and Gretchen's cousin, who becomes close friends with Drew. A spirited, rebellious, and fearless tomboy, Whitley is the first to discover that Drew is a werewolf and Lyssia's only hope to restore the balance. •
Kobna Holdbrook-Smith as: • Master Hogan (Season 1), the scoutmaster of Brackenholme and Whitley's mentor • Lord Orsino, an ally and cousin of King Leopold, who is among the catlords that rule the continent of Bast • Zadka Korga (Season 2), an elderly Romari traveler •
Paterson Joseph as Duke Bergan, the bearlord of Brackenholme and father of Broghan and Whitley, who is sworn to protect the future wolf king •
Samuel Anderson as Broghan, Bergan's son and Whitley's older brother, who is fiercely protective of his home and family •
Tom Rhys Harries as Prince Lucas, a lionlord and King Leopold's arrogant and selfish son who is betrothed to Gretchen • Chris Lew Kum Hoi as Hector, the intellectual apprentice of Vankaskan, who becomes Drew's friend and confidante •
Georgia Lock as Lady Gretchen, known as the Rose of Hedgemoor, a werefox betrothed to Prince Lucas, who is initially stuck-up and spoiled, but shows a good deal of spunkiness and courage. At first, she looks down on Drew as a "mongrel", but Gretchen eventually warms up to him and comes to accept Drew as the true wolf king. •
Colin Ryan as: • Vincent, Hector's conniving younger brother, who is loyal to King Leopold and seeks to rule Redmire himself • Lord Conrad (Season 2), the horselord of Cape Gala •
Ralph Ineson as King Leopold, the lionlord of Highcliff and Prince Lucas' father. Originally from Bast, he is the tyrannical ruler of the continent of Lyssia and the main antagonist of the series. •
David Dawson as Count Vega, a sharklord and former ruler of the Cluster Isles. He now lives a life of piracy aboard his ship, the
Maelstrom. •
Rasmus Hardiker as: • Earl Mikkel, a staglord and Manfred's younger brother • Ringlin (Season 2), the captain of the Boarguard and Hector's bodyguard •
Anna Savva as Baba Korga (Season 2), the spiritual leader of a group of Romari travelers •
Paul Antony-Barber as Baron Ewan (Season 2), the former ramlord of Haggard and a skilled magister ==Episodes==