The team was founded in 2013 by a merger of two
PLFA teams,
Giants Wrocław and
Devils Wrocław. In 2014, the club played in the
Polish Bowl for the first time, where they lost to
Seahawks Gdynia. In 2016, the Panthers dominated every game and won their first Championship. The Panthers won the title by defeating Seahawks, 56–13. After the Panthers won also the 2017 Polish Bowl, the team left the
Polish American Football League and joined the new
Liga Futbolu Amerykańskiego. In first two seasons in LFA, Panthers won every game in regular season, lost Polish Bowl XIII to Lowlanders Białystok 14–13 in 2018 and won Polish Bowl XIV to Lowlanders 28–14 (both final games were played at Wrocław Olympic Stadium). The Panthers also became the first Polish team to win the
IFAF Europe Champions League. During the
COVID-19 lockdown, Jakub Samel was named new head coach of the Panthers Wrocław. He is the first Polish head coach in club history. It was also announced that the club would be one of the first 8 to join the new
European League of Football that is set to start in June 2021. ==Uniforms==