Wurlitzer Building may refer to the following buildings in thc United States:Wurlitzer Building, now The Siren Hotel, in Detroit, Michigan Wurlitzer Building (California), on Broadway in downtown Los Angeles North Tonawanda Barrel Organ Factory, in North Tonawanda, New York Wurlitzer Building at 116–122 West 42nd Street, New York City, whose design was influenced by Bush Tower Wurlitzer Flats Building, at 674 Main Street, Buffalo, New York, a unique blend of architectural grandeur and contemporary sophistication designed by architect by Edward Kent in 1895.