Wyoming Highway 161 is a highway that begins its west end at
US 85 and the eastern terminus of
WYO 152 just east of the town of
Yoder (WYO 152 continues west). WYO 161 heads east, turns north briefly at approximately 3 miles, but quickly turns back east. For its entire length, WYO 161 travels through farmland and only intersects county and local roads. Highway 161 reaches its end at
WYO 92 in the community of
Huntley. == Major intersections ==