Handedness A 2012 literature review showed that
morphometry studies had consistently found that
handedness-related effects corresponded to the extent of the Yakovlevian torque; increased torque, as measured by increased size of the right-frontal petalia and the left-occipital petalia, tends to be more common in right-handed individuals. Individuals with mixed-handedness or left-handedness show reduced levels of Yakovlevian torque. A larger analysis of 17,141 individuals' brains, including over 500 left-handed individuals, found no associations between handedness and brain asymmetry.
Developmental stuttering Reduced right-frontal and left-occipital petalias and reversed petalia asymmetries (that is, left-frontal and right occipital petalias) have been associated with developmental
stuttering in both adults and pre-adolescent boys. This may be tied to the
lateral sulcus housing
Broca's area, which plays a significant role in
production of language.
Bipolar disorder Increased size of the left-occipital petalia, resulting from an abnormally high degree of Yakovlevian torque has been associated with
bipolar disorder. Maller et al. 2015 found that increased asymmetry of the occipital lobe, or occipital bending, was four times more prevalent in subjects with bipolar disorder than in healthy controls. This applied both to patients with
bipolar disorder type I and
type II. ==Development and evolution==