Pittsburgh Pirates De Los Santos signed with the
Pittsburgh Pirates organization in July 2014 for a $100,000
signing bonus as an international free agent from the Dominican Republic. and had
Tommy John surgery and missed the 2016 minor league season. In May 2019, he was promoted to the
Greensboro Grasshoppers. He did not play in a game in 2020 due to the cancellation of the minor league season because of the
COVID-19 pandemic. In 2021, De Los Santos pitched for the
Altoona Curve and
Indianapolis Indians, while missing most of the season with a forearm injury. Following the 2021 season, he was eligible for free agency, but re-signed with the Pirates for the 2022 season. On April 13, 2022, De Los Santos combined with
Chase De Jong and
Austin Brice to throw a
no-hitter for the
Indianapolis Indians of the
Triple-A International League. On May 22, the Pirates selected De Los Santos's contract, promoting him to the major leagues for the first time. He made his MLB debut on May 25. On August 12, De Los Santos was placed on the 60-day injured list with a right shoulder
latissimus dorsi muscle strain. In 26 appearances for Pittsburgh in his rookie campaign, De Los Santos registered an 0–3 record and 4.91 ERA with 26 strikeouts and 3 saves in innings pitched. De Los Santos was optioned to Triple-A Indianapolis to begin the 2023 season. In 22 games for the Pirates, he logged a 3.33 ERA with 18 strikeouts in innings of work. Following the season on November 2, 2023, De Los Santos was removed from the 40–man roster and sent outright to Triple-A Indianapolis. He elected free agency on November 6.
New York Yankees On November 21, 2023, De Los Santos signed a minor league contract with the
New York Yankees organization. He made 51 appearances for the Triple–A
Scranton/Wilkes-Barre RailRiders in 2024, compiling a 4.12 ERA with 55 strikeouts and 4 saves across 59 innings pitched. On November 3, 2024, the Yankees added De Los Santos to their 40–man roster to prevent him from reaching minor league free agency. De Los Santos was optioned to Triple-A Scranton/Wilkes-Barre to begin the 2025 season. He made 25 appearances for New York during the regular season, compiling an 0-1 record and 3.28 ERA with 28 strikeouts across innings pitched. De Los Santos was again optioned to Triple-A Scranton/Wilkes-Barre to begin the 2026 season. ==See also==