Main •
Ana María Orozco as Beatriz "Betty" Aurora Pinzón Solano; A rather uncouth woman but very skilled in economics with a good CV. Later becomes a CEO assistant and economist. She is the pride of her parents. She is in love with Armando Mendoza. •
Jorge Enrique Abello as Armando Mendoza Sáenz; Eco Moda's CEO. A somewhat irresponsible playboy with only basic knowledge in industrial engineering who presents a risky and ambitious proposal with which he wins the presidency of Eco Moda. When he manages it, it brings the company to the brink of bankruptcy, thus Betty steps in to help. Despite being a completely superficial playboy, he sincerely falls in love with Betty, seeing beyond her ugliness. •
Natalia Ramírez as Marcela Valencia; Armando's fiancée and Eco Moda's stockholder and retail manager. Despite her dislike of Betty, she is not actually a bad person, but a woman full of pride, classism and lacks dignity, and she loves Armando. She later willingly gives up on him as she discovers he actually loves Betty. •
Lorna Cepeda as Patricia Fernández; Marcela's best friend and secretary. A divorced woman, refined and superficial, as well as materialist, she is looking for a rich husband. Armando hates her because she is a
dumb blonde and knows that Marcela wants her as Armando's secretary to watch over his infidelities. • Luis Mesa as Daniel Felipe Valencia; Marcela's brother. Male chauvinist and arrogant, shareholder of Eco Moda. He rivals and dislikes Armando and unlike him, he is realistic and the only one worried about his company. He has an affair with Patricia. •
Julián Arango as Hugo Lombardi; Eco Moda's fashion designer. Openly gay and arrogant, who despises ugliness. He dislikes almost everyone at Eco Moda and especially hates Eco Moda's secretaries, whom he nicknames 'The Ugly Cuartel', with the exception of Inesita who is perhaps the only person he actually cares for. Arango was married to Ana María Orozco during the recording. •
Ricardo Vélez as Mario Calderón; Armando's best friend and Eco Moda's commercial vice president. A staunch playboy, inveterate enemy of commitments and fatherhood, he is strangely enough a rather neutral figure. •
Mario Duarte as Nicolás Flaminio Mora Cifuentes; Betty's best friend and economist. Like Betty, he is unattractive and highly intelligent. He is in love with Patricia and boasts of his position as president of Terramoda. Patricia softens to him but only because of his newfound wealth. •
Kepa Amuchastegui as Roberto Mendoza; Armando's father, founder of the company. Kind hearted and intelligent. •
Talú Quintero as Margarita Sáenz de Mendoza; Armando's mother. •
Adriana Franco as Julia Solano Galindo de Pinzón; Betty's mother. Loves her daughter dearly. •
Jorge Herrera as Hermes Pinzón Galarza; Betty's father and accountant. •
Pilar Uribe as María Beatriz Valencia; Marcela's and Daniel's sister. Carefree woman who loves opulence. • Julio César Herrera as Freddy Stewart Contreras; messenger, infatuated with Aura Maria and also in love of Jenny. Flamboyant but not gay, he is a very happy man. •
Dora Cadavid as Inés "Inesita" Ramírez de Muriel; seamstress, member of the cuartel. Kind and wise, she is the elderly assistant to Hugo Lombardi who loves her like a mother. She is the voice of reason and is as sane as Betty in the cuartel. •
Estefanía Gómez as Aura María Fuentes Rico; receptionist, member of the cuartel. Single mother looking for a husband and stepfather for her son. Beautiful and voluptuous, she is usually promiscuous but with a big heart. •
Paula Peña as Sofía López de Rodríguez; secretary, member of the cuartel. Divorced woman who constantly fights with her ex-husband Efraín over their children's pension. She has a feud with Jenny, the current romantic partner of her ex-husband. Formerly Gustavo Olarte's secretary and after his dismissal, she temporarily becomes Betty's secretary. •
Luces Velásquez as Bertha Muñoz de González; Gutiérrez' secretary, somewhat gluttonous, member of the cuartel. She is married with children and deeply loves her husband. She occasionally imitates Patricia's way of dressing. •
Marcela Posada as Sandra Patiño; Calderón's secretary, member of the cuartel. Known for her height. She is usually aggressive with whoever is the enemy of the cuartel. •
María Eugenía Arboleda as Mariana Valdés; Marcela's secretary, member of the cuartel. Known for reading tarot, she is very optimistic and a lover of rumba. •
Celmira Luzardo as Catalina Ángel; Betty's "fairy godmother" and public relationist. A dignified, loquacious, eloquent and recognized woman. •
Alberto León Jaramillo as Saúl Gutiérrez; Eco Moda's Director of Human Resources. Pedantic and smug man who also despises ugliness and is known for his "Spanglish". He usually sides with whoever is in charge. •
Marta Isabel Bolaños as Jenny García; Efraín's younger girlfriend. Attractive but quite dimwitted and materialistic, she rivals Sofía for Efraín's money. She calls Efraín "
pupuchurro". • David Ramírez as Wilson Sastoque Mejía; Eco Moda's security guard and friend to Betty and her friends. •
Raúl Santa as Efraín Rodríguez Merchán "El Cheque"; Sofia's ex-husband and Jenny's boyfriend. •
Patrick Delmas as Michel Doinel; Betty's handsome friend and suitor. He is in love with Betty, to whom he offers a stable relationship without caring that she is virtually ugly. •
Diego Cadavid as Román; a street rat.
Recurring •
Alberto Valdiri as "Gordito" González, Bertha's husband. •
Angeline Moncayo as Karina Larson. Formerly a model and Armando's ex-mistress. •
Carlos Serrato as Gustavo Olarte, Eco Moda's ex-financial vice president. Daniel's right hand. •
César Mora as Antonio Sánchez, Betty's lawyer. • Claudia Becerra as Mónica Agudelo. •
Diego Vivanco as Rolando "el Chesito su mercé", Hugo's boyfriend. • Germán Tóvar as José Ambrosio Rosales; lawyer, Antonio's colleague. • Hugo Perez as Rafael Muriel, Inesita's ex-husband. • Iván Piñeros as Jimmy Fuentes (Aura María's son). •
Lorena McAllister as Diana Medina. •
Luis Enrique Roldán as Juan Manuel Santamaría, penalist Eco Moda's lawyer. • Miguel Ángel Báes as a 2nd systems engineer. • Paulo Sánchez Neira as Miguel Ortíz, Eco Moda's ex-systems engineer at the service of Olarte. •
Rubén Óliver as Miguel Robles, corrupt president of Rag Tela. •
Sebastián Sánchez as Miguel. (2001) •
Scarlet Ortiz as Alejandra Zingg. •
Yesenia Valencia as Susi. • Verónica Ocampo as Claudia Bosch, an attractive model obsessed with Armando since both had an affair. •
Vilma Vera as Maruja Bravo de Gutiérrez, Saul Gutiérrez's wife. == Sequels and spin-offs ==