Scholarly estimates have varied substantially for the pre-contact populations of most native groups in California, as historians and anthropologists have tried to evaluate early documentation.
Alfred L. Kroeber estimated the 1770 population of the Yuki proper,
Huchnom, and Coast Yuki as 2,000, 500, and 500, respectively, or 3,000 in all.
Sherburne F. Cook initially raised this total slightly to 3,500. Subsequently, he proposed a higher estimate of 9,730 Yuki. According to the research of Benjamin Madley, "the Yuki suffered a cataclysmic population decline under United States rule. Between 1854 and 1864, settlement policies, murders, abductions, massacres, rape-induced venereal diseases, and willful neglect at Round Valley Reservation reduced them from perhaps 20,000 to several hundred." Intermarriage among neighboring tribes after their forced relocation to the Round Valley Reservation resulted in large numbers of Native Americans with mixed ancestry. Many of these people are descendants of many local tribes and have come to be called Round Valley Indian Tribes. In the 2010 census, 569 people claimed Yuki ancestry. 255 of them were full-blooded. ==Ethnobotany==