Shooto Sasaki started his professional career in 2010. He fought mainly for
Shooto, but also fought for
Deep and GCM early in his career. Sasaki faced Yo Saito on December 18, 2010, at
Shooto: The Rookie Tournament 2010 Final. He defeated Saito via unanimous decision after two rounds and became the 2010 Shooto 143-pound rookie champion. Sasaki faced Tetsu Suzuki on January 20, 2013, at
Shooto: 1st Round 2013 for the Shooto Pacific Rim 132-pound title. He won via unanimous decision and became the new champion. Sasaki defended his title on July 27, at
Shooto: 3rd Round 2013 against Kenji Yamamoto. He won via knockout at 11 seconds in the first round and retained the title. Shortly after the bout, Sasaki relinquished his title in order to be able to fight for Shooto's world title. Sasaki faced current
ZST 132 lb champion
Keisuke Fujiwara on January 13, 2014, at
Shooto: 1st Round 2014. He won via submission due to a rear-naked choke in the first round.
Ultimate Fighting Championship In July 2014, it was announced that Sasaki had signed with the UFC. He made his debut against
Roland Delorme at
UFC Fight Night 48 on August 23, 2014. Sasaki won via submission in the first round. The win also earned Sasaki his first
Performance of the Night bonus award. Sasaki faced
Leandro Issa on December 20, 2014, at
UFC Fight Night 58. He lost the fight by submission in the second round. Sasaki faced
Taylor Lapilus on June 20, 2015, at
UFC Fight Night 69. He lost the fight via TKO in the second round. Sasaki faced
Willie Gates May 8, 2016, at
UFC Fight Night 87. He won the fight via submission in the second round. Sasaki was expected to face
Matheus Nicolau on November 19, 2016, at
UFC Fight Night 100. However, on November 3, Nicolau was pulled from the bout after
USADA revealed a potential anti-doping violation from a sample taken October 13. Sasaki next faced
Wilson Reis on February 11, 2017, at
UFC 208. He lost the fight by unanimous decision. Sasaki faced
Justin Scoggins on June 17, 2017 at
UFC Fight Night: Holm vs. Correia. Sasaki suffered almost two rounds of damage but managed to sink his arm around Scoggins' neck and submitted him via a rear-naked choke in the second round to win the fight. This fight won Sasaki his second
Performance of the Night bonus award. Sasaki faced
Jussier Formiga on September 23, 2017 at
UFC Fight Night: Saint Preux vs. Okami. He lost the fight via submission in the first round. Sasaki was scheduled to face
Magomed Bibulatov on April 21, 2018 at
UFC Fight Night 128. However, Bibulatov was removed from the card due to back injury, and the bout was cancelled. Sasaki faced
Jenel Lausa on June 23, 2018 at
UFC Fight Night 132. He won the fight in round two via a rear-naked choke submission. Sasaki faced
Alexandre Pantoja on November 17, 2018 at
UFC Fight Night 140. He lost the fight via rear-naked choke submission in the first round.
Rizin FF Sasaki faced
Manel Kape in a 130lbs catchweight bout at
Rizin 14 on December 31, 2018. He won the fight by unanimous decision. Sasaki was then scheduled to face
Kai Asakura at
Rizin 15 on April 21, 2019. However, Sasaki was forced to withdraw from the bout due to a visceral injury and was replaced by
Justin Scoggins. He then faced
Shintaro Ishiwatari at
Rizin 17 on July 28, 2019. Sasaki lost the fight via second-round submission. The fight with
Kai Asakura was then rebooked to take place at
Rizin 19 on October 12, 2019. Sasaki lost the fight via first-minute technical knockout due to a broken jaw. After recovering from two jaw surgeries to repair the damage sustained in his previous fight, Sasaki faced Kenta Takizawa at
Rizin 26 on December 31, 2020. He won the fight via unanimous decision. Sasaki faced Yoshinori Horie at
Rizin 30 on September 19, 2021. He lost the bout via unanimous decision. Sasaki headlined
Rizin Trigger 2 on February 23, 2022 against
Kleber Koike Erbst. Even after finding initial success with the stand-up in the first round, Sasaki lost the bout in the second round via rear-naked choke. Sasaki was expected to face Yoshiki Nakahara at
Rizin 37 on July 31, 2022. He withdrew from the fight on July 26, after he tested positive for
COVID-19. Sasaki faced Boyd Allen at
Rizin 42 on May 6, 2023. He won the fight by unanimous decision. ==Professional wrestling career==