Zeng's research is mainly focused on medical genetics and
developmental biology. In July 2009 Zeng, her co-workers, and her co-operational team published a paper in
Nature, demonstrating for the first-time that an entire
mammalian body can be generated from
induced pluripotent stem cells (iPSCs). They used
mouse embryos and created iPSCs by applying the same method as
Shinya Yamanaka's team. They further created
tetraploid embryos by fusing two early-stage
fertilized embryos. They implanted these embryos and some of them finally developed into full mice. Twelve mice even
mated and produced
offspring, which showed no physical deficiencies. ==See also==