Zygote is the debut studio album by American singer-songwriter John Popper. Produced by Terry Manning, it was released on September 7, 1999, less than a month after the death of bassist Bobby Sheehan. Accompanying Popper on the album were drummer Carter Beauford and guitarist Crugie Riccio, keyboardist Rob Clores and bassist Dave Ares. It peaked at No. 185 on the Billboard 200.