Main •
François Arnaud as Manfred Bernardo, a psychic who moves to Midnight trying to outrun trouble that is following him. •
Arielle Kebbel as Olivia Charity, a freelance assassin with as many secrets as guns she owns, and wife of Lemuel. •
Peter Mensah as Lemuel "Lem" Bridger, a vampire with a dark past who first came to Midnight in the 1950s and never left, and Olivia's husband. •
Dylan Bruce as Bobo Winthrop, the human proprietor of Midnight Pawn, landlord to Lemuel, Olivia, and Manfred. Also, the best friend of Fiji, later her boyfriend. •
Parisa Fitz-Henley as Fiji Cavanaugh, a quirky free-spirited witch who owns Midnight's magic shop and struggles to come to terms with how powerful she really is. •
Jason Lewis as Joe Strong, a
fallen angel who has prophesied darkness heading towards Midnight and husband of Chuy, who admonishes him for revealing his angelhood to others. •
Sarah Ramos as Creek Lovell (season 1; special guest, season 2), the mortal "girl next door beauty" waitress and gas-station attendant who becomes the love interest of Manfred, much to her father's distaste. Eventually, she reaches her limit with Midnight, and leaves town in "Head Games". She returns in "No More Mr. Nice Kai" but was later killed. •
Yul Vazquez as Reverend Emilio Sheehan (season 1; special guest, season 2), a quiet weretiger who presides over the Wedding Chapel and Pet Cemetery and their Midnighter patrons. He leaves Midnight in "To Witch Hell and Back" after Kai removes his weretiger curse.
Recurring • Joanne Camp as Xylda, a former psychic and Manfred's grandmother and con-partner who now appears as a ghost to watch over him. She moves on after her tether to the world is broken. •
Kellee Stewart as Simone Davis/Madonna Reed, a fierce protector of her fellow Midnighters, and waitress and bartender at Midnight's Home Cookin' diner. It is revealed in season two she was operating under a fake name while spying on Olivia and she leaves town. •
Bernardo Saracino as Chuy Strong, a half-
demon who, along with his husband, Joe, fears others will find out what they are. He is killed by Joe in season two. • Bob Jesser as Shawn Lovell (season 1), the owner of Midnight's Gas 'N Go, who is an overly protective father to his children and distrusts Manfred. • John-Paul Howard as Connor Lovell (season 1), the younger brother of Creek, who is as protective of her as she is of him. He harbors a secret of his own. •
Ryan McCartan as Jeremy (season 1), Fiji‘s boyfriend who she accidentally killed. • Joe Smith as Mr. Snuggly (real name Jedediah), Fiji's talking
familiar cat, who was previously the human lover of her aunt Mildred whom she turned into a cat to protect him. •
Nestor Carbonell as Kai Lucero (season 2), one of the owners of Midnight's new hotel, along with his wife Patience. Their sudden arrival in town causes a stir and has the Midnighters suspicious about what is really going on. •
Jaime Ray Newman as Patience Lucero (season 2), one of the owners of Midnight's new hotel, and Kai's wife. •
Josh Kelly as Walker Chisum (season 2), an openly gay demon hunter who has an intense connection with Joe Strong. ==Episodes==