On 27 June 2018 the brigade was formed in
Lviv Oblast. On 16 October 2018, as part of a working trip to
Lviv Oblast, the then President,
Petro Poroshenko, took part in several events dedicated to the
Day of Territorial Defense Soldiers, which took place at the International Center for Peacekeeping and Security. Poroshenko inspected the bases used for training
territorial defence battalions, in particular the personnel of the 64th Territorial Defense Battalion of the 103rd Independent Territorial Defense Brigade of the Lviv Oblast. From 17 to 20 July 2019, about two hundred reserve officers of the brigade underwent combat training at the International Center for Peacekeeping and Security.
Operations in Donetsk Oblast Units of the 103rd Brigade began performing combat operations in the
Donetsk Oblast in March 2022. On 3 September 2022, the brigade's 63rd Battalion participated in the capture of the village of
Ozerne in
Donetsk Oblast. The brigade has also been credited with capturing the village of in the Donetsk Oblast during September 2022. In early October, the brigade took up defensive positions near
Kupiansk. As of March 2023, units of the brigade were still operating in the
Serebriansky forest near the village of Yampil, namely the brigade's 63rd, 65th, and 66th Battalions.
2024 Ukrainian invasion of Kursk In 2024, units of the brigade were relocated to the
Sumy Oblast in order to defend the Ukrainian border, and later began participating in the
Ukrainian operations in Russia's
Kursk Oblast from the beginning of August. In September and October 2024, it was reported that the 103rd Brigade was participating in
Ukrainian operations in Russia's
Kursk Oblast. Units of the brigade took part in a mid-September battle in the village of . On December 11, 2024, a fighter of the brigade's anti-aircraft battery, who served for more than two years in the combat zone, but then left the unit without permission, accused the head of the brigade's air defense, Colonel Valentyn Kozakevych, of sabotaging the preparation of equipment, misappropriating the property of military personnel, and undermining the combat capability of the air defense unit. He also accused him of incompetence, citing examples of Kozakevych's demands: during the period of redeployment from one frontline region to another, he demanded to move in columns in places where there was an immediate threat of damage by rocket and artillery fire, demanded the accumulation of personnel in areas where the Russians hit with KABs, Shaheds and missiles. == Structure ==