• March –
Mary Seacole opens the British Hotel at
Balaklava, a nursing and
convalescent establishment for
Crimean War officers. • October – The
Renkioi temporary hospital,
prefabricated in wood to a design by
I. K. Brunel, is erected in
Turkey to serve Crimean War invalids. •
Thomas Addison describes
Addison's disease in
On the Constitutional and Local Effects of Disease of the Suprarenal Capsules. • The
third plague pandemic breaks out in
Yunnan, China. This
bubonic plague pandemic eventually spreads to all inhabited continents, and ultimately leads to more than 12 million deaths in
India and China (estimated 15 million worldwide) making it one of the
deadliest pandemics in history. The pandemic is considered active until 1960. ==Paleontology==