On 6 June,
Lillestrøm scored three goals in four minutes and 24 seconds, two of them in
injury time, to go from 3–0 down to 3–3 away at
Molde.
Sandefjord lost 5–0 away to
Odd Grenland on 26 September. This was their 23rd consecutive top flight match without winning, breaking a record of 22 set by
Os in
1975. The streak would continue for four matches, ending at 27 before
Sandefjord won in their 28th attempt on the last day of the season, beating
Hønefoss 6–1 at home. On 31 October,
Rosenborg played
Kongsvinger to a 0–0 draw away, making 2010 the second consecutive season without away losses for Rosenborg.
Kongsvinger and
Sandefjord were relegated at the end of the 2010 Tippeligaen season after finishing in the bottom two places of the league table. Sandefjord ended a two-year tenure at the highest football level of Norway, while Kongsvinger returned to the 1. divisjon after just one season. They were replaced by
2010 1. divisjon champions
Sogndal and runners-up
Sarpsborg 08. Sogndal returned to the Tippeligaen after a six-year hiatus, while Sarpsborg 08 made its debut at the Norwegian top-level league.
Hønefoss as 14th-placed Tippeligaen team had to compete in a
relegation/promotion playoff with the 1. divisjon teams ranked third through fifth (
Fredrikstad,
Løv-Ham and
Ranheim) for one spot in the 2011 Tippeligaen. This spot was taken by Fredrikstad, who defeated Hønefoss 8–1 on aggregate in the playoff finals and returned to Norway's top flight after just one season. In turn, Hønefoss had to return to the 1. divisjon, also after just one season. == Teams ==