Internacional Internacional qualified to the Copa Libertdores as the
2009 Campeonato Brasileiro Série A runner-up. They were drawn into Group 5 of the
Second Stage along with Ecuadorian clubs
Deportivo Quito and
Emelec, and Uruguayan club
Cerro. Their first group play match was at home against Emelec. After falling behind in the games,
Nei and
Alecsandro both scored to secure the win. They drew their next two games away at Deportivo Quito and Cerro, respectively, 1–1 and 0–0.
Giuliano scored for Inter against Deportivo Quito. Their fourth game, back at home against Cerro, ended in a 2–0 win. Alecsandro scored for Internacional after
Walter Ibáñez scored into his own net. Emelec held Internacional to a 0–0 draw in
Guayaquil. Internacional won their last game 3–0 against Deportivo Quito at home.
Andrezinho,
Bolívar, and Alecsandro scored for Inter. Internacional finished first in their group and secured the 6 seed for the knockout stages. They were the only team from Group 5 to advance. Internacional's Round of 16 opponent was Argentine club
Banfield. The first match between the two ended in a 3–1 loss.
Kléber scored Inter's only goal of the game. Back at home for the second leg, Inter beat the Argentine's 2–0 with goals by
Alecsandro and
Walter. Inter advanced to the quarterfinals thanks to Kléber's away goal in the first leg. Their next opponent was the defending champion, Argentine club
Estudiantes de La Plata. They won the first leg at home 1–0 with a goal by
Gonzalo Sorondo. The second leg, in
La Plata, ended in defeat by a score of 2–1.
Giuliano scored Inter's only goal, which was enough to advance by away goals.
São Paulo was Inter's semifinal opponent. The first leg, played at home, ended in a 1–0 win with a goal by Giuliano. As in the quarterfinals, Inter lost away 2–1. The away goal
Alecsandro sealed their slot in the finals.
Guadalajara Guadalajara's had an automatic slot in the Round of 16 as the 13 seed. Their slot came as a compromise after the fallout of the
2009 flu pandemic during the
2009 Copa Libertadores. Their Round of 16 opponent was Argentine club
Vélez Sársfield. The first game was won 3–0 with two goals by
Omar Bravo and a goal from the penalty spot by
Héctor Reynoso. The second leg was lost 2–0 back in Buenos Aires. Chivas advanced by goal difference. Their quarterfinals opponent was Paraguayan club
Libertad. The scores for both legs mirror: 3–0 home and 2–0 away. Their goals in the first leg were two by
Omar Bravo and
Ricardo Michel Vázquez. Again, they advanced by goal difference. Their semifinal opponent was Chilean
Universidad de Chile. Their first game ended in a 1–1 draw at home.
Omar Arellano scored for Chivas in the game. The second, away in Chile, ended in a 2–0 win with goals by
Xavier Báez and
Jonny Magallón. The ended 4 to 1 on point and Chivas earned their place in the finals.
Knockout stages summary ==Background==