MotoGP class Jorge Lorenzo was crowned MotoGP World Champion for the first time, after he finished third in the
Malaysian Grand Prix on 10 October. Finishing on the podium in 16 of the 18 races – including nine victories – to be held during the season, Lorenzo amassed a record points total for the premier class, achieving a total of 383 points, ten more than the previous best score achieved by
Valentino Rossi in . Second in the championship was
Dani Pedrosa, 138 points behind Lorenzo, recording four race victories over the course of the season. He and third-placed Rossi both missed at least three races due to injuries suffered during race weekends; Pedrosa suffered a fractured collarbone at
Motegi, while Rossi suffered a broken leg at
Mugello, resulting in the first missed races of his entire Grand Prix career. The only other rider to win races during the season was
Casey Stoner, who finished fourth in the championship. Stoner won three races in the latter half of the season, winning the inaugural race in
Aragón, as well as the races at Motegi and his home race at
Phillip Island.
Moto2 class Nine different riders won races in the secondary Moto2 championship, and former MotoGP rider
Toni Elías claimed the inaugural championship title, with three events to spare as his seven victories had taken him out of reach of his rivals. Second place went to
Julián Simón, who despite not winning a race, finished on the podium eight times. Third place in the championship went to
Andrea Iannone, who achieved three victories but lost out on runner-up in the championship to Simón by just two points. The season was also tinged with tragedy as the inaugural race winner in the class,
Shoya Tomizawa, died of injuries suffered in an accident at
Misano; the first on-track fatality at Grand Prix level since
Daijiro Kato was killed in the senior class at
Suzuka in . Other riders to win races were
Jules Cluzel,
Yuki Takahashi,
Roberto Rolfo,
Alex de Angelis,
Stefan Bradl and
Karel Abraham.
125cc class Spanish riders once again dominated the 125cc championship, with a 26-race winning streak for Spanish riders only being broken by
Bradley Smith at the final race of the season in
Valencia. The top three championship placings went to Spanish riders as
Marc Márquez won the championship ahead of
Nicolás Terol and
Pol Espargaró. With ten victories, Márquez became the second youngest World Champion ever at the age of , with only
Loris Capirossi's triumph coming at a younger age. ==2010 Grand Prix season calendar==