November The Ospreys carried their previous season's momentum right into their first game by earning a road upset of Illinois by a score of 93–81. In a game that UNF never trailed, the Ospreys set a program record (at the time) for three-point-shots made with 17. It was the program's second victory over a
Big Ten Conference opponent, with the first coming in December 2014 at
Purdue. In their home opener, the Ospreys blew out Texas–Rio Grande Valley, 106–84. For the second straight game they connected on 17 three-point-shots, tying the program record. They improved to 2–0 for the first time since the 2005–06 season. It was just the third time UNF has reached 100 points since joining Division I. Guard Dallas Moore recorded his second straight
double-double and became UNF's 11th player to score 1,000 career points. On November 18, coach Matthew Driscoll surpassed
Matt Kilcullen to become the winningest coach in program history with a 98–69 win over crosstown rival and
NAIA member Edward Waters. With the win, UNF started the season 3–0 for the first time since the 1994–95 season when they were members of Division II. Over the next two games, the Ospreys trailed at halftime by only two points at Louisville and one point at Saint Louis, however, they went on to lose those games by margins of 28 and 13 respectively. They won three consecutive games to finish November with a record of 6–2.
December On December 2, Moore and Beech each scored 31 points (a career high for Beech) in a 108–119 loss at LSU. The Ospreys led 56–48 at halftime, but 43 points by freshman phenom
Ben Simmons proved too much for UNF to handle. The Ospreys once again set a program record for three-point-shots made with 19. In their next game, they trailed at Dayton by only three points at halftime, but lost by a margin of 15. On December 12 against Coastal Georgia, the Ospreys scored the most points in program history with a 117–71 victory. In December, North Florida swept a four-game home stand to extend their winning streak at UNF Arena to 14 games, a program record. The Ospreys then lost two in a row at Arkansas and at VCU to close out the month of December.
January On January 2, the Ospreys won at Eastern Michigan, 82–77, to finish their non-conference schedule with a record of 11–6. In the game, senior forward Demarcus Daniels set the program record for career blocks with 146. Their 11 wins marked the most non-conference victories in program history. On January 9, the Ospreys defeated crosstown rival Jacksonville for the fifth time in a row in the
River City Rumble. On January 16, the Ospreys defeated Kennesaw State, 93–78, despite trailing by 14 points in the first half. In the game, guard Beau Beech scored a career high 33 points, and UNF extended its home winning streak to 17 games. On January 24 in a win at NJIT, the Ospreys made a program record 20 three-point-shots, a record that was broken or tied four times in the 2015–16 season.
February The Ospreys had improved to 7–0 in conference play until losing at home to Stetson on February 1. The loss snapped an 18-game home winning streak. The Ospreys lost the following three games, all on the road, to fall into a three-way tie for first place in the A-Sun at 7–4. They snapped their losing streak by defeating NJIT at home, 107–71 on February 18. On February 20, the Ospreys clinched at least a share of the Atlantic Sun regular season title by defeating USC Upstate, 81–78. They secured the regular season championship and No. 1 seed in the Atlantic Sun Tournament with a win at crosstown rival Jacksonville.
March The Ospreys began their quest to win back-to-back Atlantic Sun Tournament titles by defeating USC Upstate in the quarterfinals, 92–69. However, they were blown-out by 33 points in the semifinals by Florida Gulf Coast. Their 56 points were the fewest they scored in any game this season. Due to renovations at the
O'Connell Center, the 7-seed Ospreys hosted the 2-seed
Florida Gators in the first round of the
2016 National Invitation Tournament, where they fell 97–68 in front of 6,011 fans at the UNF Arena. Source:
NOTES: :Game postponed from Saturday, January 23 at 4 pm to Sunday, January 24 at 6 pm due to
Winter Storm Jonas. == Awards and honors ==