On 15 July 2021, the FFF ratified the constitution of the competition, and published the groups. Due to the non-completion of the
2020–21 season, the FFF declared that there would be no regular promotion or relegation from the division, and that any vacancies to be filled would be done on the basis of finishing positions in the 2019–20 season. Changes from 2020–21 season are as follows: •
Sedan were promoted to Championnat National to replace
SC Lyon, who finished bottom of
2020–21 Championnat National, and were relegated according to the rules of that competition. SC Lyon will play as
Lyon La Duchère in Championnat National 2 this season. •
Bourges 18 and
Bourges Foot merged to form
Bourges Foot 18, resulting in a vacancy. •
Gazélec Ajaccio were administratively relegated to
Championnat National 3 for financial reasons, a decision which was confirmed on appeal, resulting in a vacancy. • Vacancies were to be filled by
Lille (res) and
Vitré as
best 14th placed teams in the 2019–20 season. However, Lille (res) declined to take up the position, and were replaced by
Montpellier (res). ==Impact of COVID-19 on the season==