The homoisoflavonoids
portulacanones A,
B,
C and
D can be found in
Portulaca oleracea (common purslane, Caryophyllales, Portulacaceae). The 3,4-dihydroxyhomoisoflavans
sappanol, episappanol, 3'-deoxysappanol, 3'-O-methylsappanol and 3'-O-methylepisappanol can be found in
Caesalpinia sappan. The homoisoflavones
scillavones A and
B can be isolated from the bulbs of
Scilla scilloides (
Barnardia japonica).
Homoisoflavanones Homoisoflavanones (3-Benzyl-4-chromanones) can be found in various plants, notably in members of the
Scilloideae.
Sappanone A can be found in
Caesalpinia sappan. C-Methylated homoisoflavanones (
3-(4'-methoxy-benzyl)-5,7-dihydroxy-6-methyl-8-methoxy-chroman-4-one,
3-(4'-methoxy-benzyl)-5,7-dihydroxy-6,8-dimethyl-chroman-4-one,
3-(4'-hydroxy-benzyl)-5,7-dihydroxy-6,8-dimethyl-chroman-4-one,
3-(4'-hydroxy-benzyl)-5,7-dihydroxy-6-methyl-8-methoxy-chroman-4-one and
3-(4'-hydroxy-benzyl)-5,7-dihydroxy-6-methyl-chroman-4-one) can be found in the rhizomes of
Polygonum odoratum.
5,7-Dihydroxy-3-(3-hydroxy-4-methoxybenzyl)-chroman-4-one, a homoisoflavanone extracted from
Cremastra appendiculata (Orchidaceae), has anti-angiogenic activities and inhibits UVB-induced skin inflammation through reduced cyclooxygenase-2 expression and NF-?B nuclear localization.
In Asparagaceae 3-(4'-Methoxybenzyl)-7,8-methylenedioxy-chroman-4-one, a homoisoflavanone with antimycobacterial activity, can be isolated from
Chlorophytum inornatum (Asparagaceae, Agavoideae). ; in Scilloideae (formerly Hyacinthaceae)
7-O-α-Rhamnopyranosyl-(1→6)-β-glucopiranosyl-5-hydroxy-3-(4-methoxybenzyl)-chroman-4-one,
7-O-α-rhamnopyranosyl-(1→6)-β-glucopiranosyl-5-hydroxy-3-(4′-hydroxybenzyl)-chroman-4-one,
5,7-dihydroxy-3-(4′-methoxybenzyl)-chroman-4-one (
3,9-dihidroeucomin),
5,7-dihydroxy-6-methoxy-3-(4′-methoxybenzyl)-chroman-4-one,
5,7-dihydroxy 3-(4′-hydroxybenzyl)-chroman-4-one (
4,4'-demethyl-3,9-dihydropuctatin),
5,7-dihydroxy-3-(4′-hydroxybenzyl)-6-methoxy-chroman-4-one (
3,9-dihydroeucomnalin) and
7-hydroxy-3-(4′-hydroxybenzyl)-5-methoxy-chroman-4-one can be isolated from the bulbs of
Ledebouria - a genus of plants plant widely used
traditional African medicine. The homoisoflavanone glycosides
(-)-7-O-methyleucomol 5-O-beta-D-glucopyranoside,
(-)-7-O-methyleucomol 5-O-beta-rutinoside and
(-)-7-O-methyleucomol 5-O-beta-neohesperidoside can be isolated from the bulbs of
Ornithogalum caudatum. Scillascillin-type homoisoflavanones (3-hydroxy-type homoisoflavonoids) can be isolated from
Drimiopsis maculata.
Eucomin,
eucomol,
(E)-7-O-methyl-eucomin,
(—)-7-O-methyleucomol,
(+)-3,9-dihydro-eucomin and
7-O-methyl-3,9-dihydro-eucomin can be isolated from the bulbs of
Eucomis bicolor.
4'-o-Methyl-punctatin,
autumnalin and
3,9-dihydro-autumnalin can be found in
Eucomis autumnalis. Five homoisoflavanones,
3,5-dihydroxy-7,8-dimethoxy-3-(3',4'-dimethoxybenzyl)-4-chromanone,
3,5-dihydroxy-7-methoxy-3-(3',4'-dimethoxybenzyl)-4-chromanone,
3,5-dihydroxy-7,8-dimethoxy-3-(3'-hydroxy-4'-methoxybenzyl)-4-chromanone,
3,5,6-trihydroxy-7-methoxy-3-(3'-hydroxy-4'-methoxybenzyl)-4-chromanone and
3,5,7-trihydroxy-3-(3'-hydroxy-4'methoxybenzyl)-4-chromanone, can be isolated from the dichloromethane extract of the bulbs of
Pseudoprospero firmifolium. A homoisoflavanone can also be found in
Albuca fastigiata. The same molecule, 5,6-dimethoxy-7-hydroxy-3-(4′-hydroxybenzyl)-4-chromanone, can be found in the bulbs of
Resnova humifusa and
Eucomis montana. == Uses ==