The brigade combat team was formally notified to prepare for a deployment in support of Operation Enduring Freedom on 19 April 2012. The brigade combat team's preparation included a Unified Endeavor Mission Command Exercise with the 3rd Infantry Division at
Fort Stewart, Georgia in May 2012; a mission readiness exercise at the National Training Center in June 2012; and a brigade-directed small unit counter-improvised explosive device validation and advanced situation awareness training exercise at Joint Base Lewis-McChord. Following pre-deployment training and soldier readiness processing, the brigade combat team completed its task organization for combat and deployed its equipment and personnel through Manas, Kyrgyzstan to the Regional Command-South Area of Operations, terminating for theater specific training at
Kandahar Airfield. It later assumed
security force assistance responsibilities from Combined Task Force Arrowhead, 3–2 SBCT, on 24 November 2012. Including the eight southern Kandahar Districts of Panjwa’i, Dand, Daman, Spin Boldak, Takteh Pol, Registan, Arghistan, and Maruf, the CTF 4–2 area of operations encompassed an area greater than 41,000 km2, approximately the size of Massachusetts and Connecticut combined. In early November, CTF 4–2 arrayed its four maneuver battalions, military intelligence battalion, brigade support battalion,
Afghan National Security Forces Assistance Teams – composed of soldiers from 4–2 SBCT; the 56th Infantry Brigade Combat Team, Texas National Guard; and the 29th Infantry Brigade Combat Team, Hawaii National Guard – and numerous other military and Department of State organizations across twenty-one pieces of tactical infrastructure. The brigade attached its cavalry squadron to the 1st Armored Brigade Combat Team, 3rd Infantry Division in Zabul province. 4th Battalion, 9th Infantry Regiment, Task Force Manchu, operated in the western portion of Panjwa’i district, known as the "Horn of Panjwa’i". Their area of operations consisted of Forward Operating Base Zangabad, Combat Outposts Mushan and Talukan, and Checkpoints Mullah Mahdi, Gerandai, and Perozi. Over the span of nine months, the 2nd Kandak, 1st Brigade, 205th Afghan National Army Security Force Assistance Team and Task Force Manchu worked with their partnered kandak daily to enhance the kandak's ability to provide security within the Horn of Panjwa’i. Upon arrival, TF Manchu and its 2nd Kandak SFAT encountered a unit that was completely dependent on International Security Assistance Forces. Eventually, 2nd Kandak – along with 6th Kandak, Afghan National Civil Order Police, Afghan national and local police, successfully completed six independent clearing operations, known as Operations Zafar. In this operation, the units discovered over eighty improvised explosive devices, and destroyed a major home-made explosive factory and numerous caches of smalls arms and other munitions. These operational successes culminated with the successful transfers of COPs Mushan and Talukan, along with Checkpoints Mullah Mahdi, Gerandai, and Perozi to the Afghan National Security Forces. 1st Battalion, 38th Infantry Regiment (TF Rosser) maintained responsibility for the central and eastern portions of Panjwa’i District, approximately 35 kilometers west of Kandahar City. TF Rosser operated out of Forward Operating Base Shoja, and Combat Outposts Sperwan Ghar and Khenjakak. TF Rosser employed two separate security force assistance teams. 6th Kandak, 1st Brigade, 205th Afghan Army SFAT and the District Headquarters-Panjwa’i SFAT provided direct mentorship and assistance to the Afghan National Security Forces in Panjwa’i. Both SFATs worked at the kandak level in a location in southern Afghanistan. TF Rosser and its partnered 6th Kandak conducted a three-week-long combined arms breach, known as Operation Winter Road. The joint Afghan and US task force completed the construction of 6.3 kilometers of road through the heart of Panjwa’i. Seven mine clearing line charges were used to create greater than fifteen sympathetic detonations. Thirty-five trees were removed to provide observation and fields of fire, with over 12,500 lbs of C4 explosive used. Forty-two pressure plate IEDs and one Hybrid RC-IED were reduced from sixteen different locations. TF Rosser exploited six caches consisting of five anti-personnel mines, two grenades, eight RPG rounds, forty-one high metal and thirty-eight carbon rod pressure plate systems, 250 rounds of AK-47 munitions and five AK-47 mags, 600 ft of lamp and detonation cord, ninety-one blasting caps, five radios, one cell phone, and over 350 lbs of HME, as well as hundreds of other IED making materials were removed from the area. During its deployment, the District Headquarters-Panjwa’i SFAT successfully transferred Panjwa’i's District Headquarters to the Afghan Uniformed Police, and the 6th Kandak SFAT at Shoja assisted in hand-over of COPs Khenjakak and Sperwan Ghar to the Afghan National Army. The efforts by both TF Manchu and TF Rosser to train and advise the ANSF units led to the improved security situation throughout Panjwa’i District, as the 2nd the 6th Army Kandaks respectively achieved "effective with advisors" and "independent with advisors" by the end of these task forces' deployments in Panjwa’i. 2nd Battalion, 12th Field Artillery Regiment, TF Viking, conducted Security Force Assistance Operations from ten separate bases spread across Kandahar, Zabul, and Farah Provinces. TF Viking executed a diverse mission, advising, training, and assisting the Afghan National Security Forces. Throughout the deployment, TF Viking coordinated parallel and partnered operations with the Daman and Dand Afghan Uniformed Police, along with the Air Force Office of Special Investigation, to interdict enemy lines of communication, prevent the flow of insurgent resources into Panjwa’i District, and interdict enemy indirect fires aimed at Kandahar Airfield, all of which were aided by SFATs' mentorship with the AUP. Together, partnered TF Viking operations reduced significant activities throughout its area of operations by thirty percent since inheriting responsibilities in November. Additionally, partnering from TF Viking and its SFATs with EOD, D-30 field artillery, logistics, and other maneuver support and sustainment training allowed the 4th Afghan Army Combat Service Kandak and the 5th Afghan Army Combat Service Support Kandak to achieve an "independent with advisors" status, resourcefully supporting and sustaining the rest of the 1st Afghan National Army Brigade throughout all of Kandahar province. Also, the Afghan Uniformed Police of Dand and Daman districts achieved the ability to operate completely independent and autonomously from ISAF advisors with the transfer of COP Edgerton and the Daman District Headquarters. 2nd Battalion, 23rd Infantry Regiment (TF Tomahawk) area of operation was Spin Boldak, Takteh Pol, and Shorabak Districts in the south eastern portion of the brigade's area of operations, known as AO Texas. Through the security force assistance teams composed primarily of soldiers from the 56th Infantry Brigade Combat Team, TF Tomahawk partnered with six separate Afghan Security Forces elements to include the 3rd Afghan Border Police Kandak; the 4th Afghan Border Police Kandak; the Takteh Pol and Spin Boldak Afghan Uniform Police; the Afghan Border Police Quick Reaction Force Kandak; and the Afghan Customs Police at the Weesh Border Crossing. TF Tomahawk's conducted numerous partnered operations, known as Operations Southern Fist and Southern Strike, with the Afghan Border Police. During Operations Southern Fist, TF Tomahawk captured two Soviet-designed ZPU anti-aircraft guns with 180 rounds of ammunition, one 82 mm, and one 75 mm recoilless rifle with twenty-two and eighteen rounds of ammunition respectively, one AK-47, three carbines, one pistol, two RPG 7 launchers with fourteen rockets, eight IEDs, 250 kg of homemade explosives and 210 fuses and remote control detonators. TF Tomahawk oversaw Afghan engineers clear numerous routes along the Afghan-Pakistan border, holding the terrain with Afghan resourced checkpoints. TF Tomahawk successfully transferred COP Lakaray and Checkpoint Two to the ANSF, allowed two Afghan Border Police kandaks to achieve complete autonomy from ISAF. 2nd Squadron, 1st Cavalry Regiment, TF BlackHawk, attached to 1st Armored Brigade Combat Team, 3rd Infantry Division, partnered with the 2nd Mobile Strike Force and the 4th Kandak, 2nd Brigade, 205th Afghan Army Corps in
Zabul Province at FOB Apache and FOB Wolverine. TF Blackhawk's troopers conducted numerous troop and squadron level training exercises and clearing operations with their Afghan partners. in Operation Blackhawk Hammer, a combined, Afghan-led operation, cleared an area of Zabul Province historically used by the Taliban to stage equipment and caches along
Afghan Highway One. The 2nd MSF staged blocking positions to allow the 4th Kandak to clear several Afghan villages of IED components and enemy fighters. Because of this and other operations with TF Blackhawk, 4th Kandak is now conducting independent operations. 702d Brigade Support Battalion deployed to Kandahar Airfield to provide logistical support to operations throughout southern Kandahar Province. The 702d BSB was task organized into six logistic support teams (LST) and three convoy security teams to support CTF 4–2 in Kandahar and 2–1 Cavalry in Zabul province. The LSTs were tailored to support twenty outlying, separate bases and provided distribution of all classes of supply from task force bases to company and platoon COPs. 702d BSB developed a rapid aerial resupply process that maximized the use of all aviation assets available resulting in the successful coordination of roughly 1,000 missions delivering over 1,300 pallets of fresh fruits and vegetables, ammunition, and repair parts to sustain combat operations for four maneuver battalions. The 702d BSB was instrumental in the retrograde and responsible draw down of CTF 4-2's and RC-South's footprint within CTF 4-2's area of operations. Throughout the nine-month OEF deployment, Raider soldiers neutralized several insurgent cells in key district areas; trained two Afghan National Army kandaks and four district police forces to the point of independent operations; facilitated friendly mobility and infrastructure development deep into traditional enemy sanctuaries, building 12 miles of road and repairing another 20; dramatically reduced requirement for International Security Assistance Force presence in what was a volatile area; enabled the local government to extend services to the population, including four major canal construction projects, three road builds, and six medical civic actions; and ultimately responsibly closed fifteen pieces of tactical infrastructure. Additionally, coupled with the growing legitimacy and influence of Government of the Islamic Republic of Afghanistan officials, the brigade noticed tangible improvements in all of its Afghan National Security Force partners. On 25 June 2013, 4–2 SBCT received notification that it will be among the twelve brigade combat teams to deactivate over the next five years in support of the Army's effort to downsize the active-duty force as the military winds down from the wars in Iraq and Afghanistan. Following its transfer of authority with the 2nd Stryker Cavalry Regiment, the Raider Brigade formally cased its colors on 11 September 2013 on JBLM. Four days later the city of Lakewood hosted a welcome home parade for the brigade and its family members. In February 2015 they were informed that they would receive a Meritorious Unit Commendation == Inactivation ==