Little-Pengelly began her political career in 2007 as
Special Advisor (Spad) to the
Reverend Ian Paisley, while he was in the office of
First Minister, where she worked as part of the DUP talks team with victims of
the Troubles. Little-Pengelly remained in the position of Special Advisor when Peter Robinson assumed the office of First Minister in 2008 until 2015 after over eight years in the position. In 2015, Little-Pengelly was chosen by the DUP to replace
Jimmy Spratt as MLA for Belfast South in the
Northern Ireland Assembly, following his retirement due to ill health. On 28 October 2015, Little-Pengelly was appointed as a junior minister in the Northern Ireland
Executive Office. At the
2017 UK general election, Little-Pengelly was elected MP for
Belfast South, gaining the seat from the
SDLP's
Alasdair McDonnell. The former Northern Ireland
First Minister Peter Robinson was the chief strategist behind Little-Pengelly's campaign. She later lost the seat to the
SDLP's
Claire Hanna at the
2019 general election. On 12 May 2022, one week after the
Northern Ireland Assembly election, DUP leader
Jeffrey Donaldson refused to take his seat in Stormont due to his opposition to the
Northern Ireland Protocol. Little-Pengelly was appointed by the DUP to replace him. She said "I have agreed to fill [Donaldson's] seat in Lagan Valley at this time both to support this work and to ensure a continued high level of support and service to the constituents of Lagan Valley. It is a privilege to be asked to fulfil this role at this important time for unionism and for Northern Ireland. While Sir Jeffrey focuses on that immediate task, I look forward to serving the people of Lagan Valley with passion and commitment."
Deputy First Minister of Northern Ireland with
Keir Starmer in July 2024 On 3 February 2024, Little-Pengelly became
Deputy First Minister of Northern Ireland following the
reestablishment of the
Northern Ireland Executive. Her appointment marked the first time a unionist occupied the office of Deputy First Minister. In July 2025, she faced controversy when she and her husband undertook a publicly-funded trip to Wimbledon; almost £1000 covered the flights and accommodation, in addition to the free seats they received in the
Royal Box. She went on the trip even though it clashed with a rearranged appearance before the
Committee for the Executive Office. ==Personal life==