Synapse In 1992 Walker and Michael Loeb co-founded New Sub Services, today known as
Synapse Group, a company that used the
credit card network to process magazine subscriptions. By 1998 Synapse had sold 30 million magazine subscriptions, with sales approaching $300 million. In 2004 and 2005, Synapse was named one of the 25 "Best Places to Work in America" among medium-sized companies by the Great Place to Work Institute. Synapse employed more than 250 people. Loeb also assisted with the early funding of Priceline. Priceline sold an estimated 40,000 tickets in its first quarter of operation. He worked with IGT to develop innovative concepts and technologies for dozens of networked
slot machines and other gaming devices, initially under a comprehensive license agreement. The first result of the partnership was
Guaranteed Play, a new method for casino game players to purchase game play. Customers receive a fixed number of slot machine spins or
blackjack hands, known as a "session" of play, at a discounted price, by paying in advance.
Perfect Pay Baccarat In 2009 Walker Digital subsidiary Walker Digital Gaming introduced the Perfect Pay
Baccarat (card game) table and Smart Table Network, supporting Elite Baccarat. Industry business journals reported that Perfect Pay utilizes
RFID technology to track baccarat wagers, hand outcomes, payouts and player ratings in real time while eliminating losses from dealer mis-pays, counterfeit chips and other problems. Perfect Pay and Elite Baccarat both won Gold Awards from Casino Journal at the 2009 Gaming Technology Summit. He later founded Upside Travel.
LabTV In 2013, Walker founded
LabTV to encourage students to consider a medical research career.
ApiJect Systems Corporation In 2018, Jay Walker and
Marc Koska co-founded
ApiJect Systems, Corp., a medical technology company that creates single-use plastic injectors. He serves as the company’s chairman. ==Patent lawsuits and disputes==