It ascends between the
sphenomandibular ligament and the
lateral pterygoid muscle, and between the two roots of the
auriculotemporal nerve to the
foramen spinosum of the
sphenoid bone, through which it enters the
cranium; it then runs forward in a groove on the great wing of the
sphenoid bone, and divides into two branches, anterior and posterior. The
anterior branch, the larger, crosses the great wing of the sphenoid, reaches the groove, or canal, in the sphenoidal angle of the
parietal bone, and then divides into branches that spread out between the dura mater and internal surface of the cranium, some passing upward as far as the
vertex, and others backward to the
occipital region. The
posterior branch curves backward on the
squamous part of the
temporal bone, and, reaching the parietal bone some distance in front of its mastoid angle, divides into branches that supply the posterior part of the dura mater and cranium. The branches of the middle meningeal artery are distributed partly to the dura mater, but chiefly to the bones; they anastomose with the arteries of the opposite side, and with the
anterior and
posterior meningeal arteries. The very smallest distal branches
anastomose through the
skull with small arterioles from the
scalp. On entering the cranium, the middle meningeal artery gives off the following branches: • Numerous small vessels supply the
trigeminal ganglion and the
dura mater • A superficial petrosal branch enters the
hiatus of the facial canal, supplies the
facial nerve, and anastomoses with the
stylomastoid branch of the
posterior auricular artery. • A
superior tympanic artery runs in the canal of the
tensor tympani muscle, and supplies this muscle and the lining of the canal. • Orbital branches pass through the
superior orbital fissure or through separate canals in the
great wing of the sphenoid, to anastomose with the
lacrimal or other branches of the
ophthalmic artery. • Temporal branches pass through foramina in the
great wing of the sphenoid, and anastomose in the
temporal fossa with the
deep temporal arteries.
Variation In approximately half of subjects, it branches into an
accessory meningeal artery. Very rarely, the
ophthalmic artery may arise as a branch of the middle meningeal artery. The middle meningeal artery may arise not only from the
maxillary artery but also from the
ophthalmic artery, or
lacrimal artery. ==Clinical relevance==