Al-Tadamun Hadramaut was founded in 1959. The club was promoted back to the
Yemeni League in 2023, following promotion from the
Yemeni Second Division the previous season. The club clinched promotion to the top division with a 5–0 victory over khanfar Abyan SC on the penultimate matchday. That year, the club also advanced to the semi-finals of the 7th annual Liberation Cup celebrating the 24 April liberation of Mukalla following the
Battle of Mukalla, ultimately being defeated by
Al-Shaab. In 2025, the club won the same competition, defeating Al-Shaab 2–1 in the final to win the title. In June 2025, it was announced that Al-Tadamun Hadramaut had been selected by the
Yemen Football Association to be the nation's participant in the
2025–26 AGCFF Gulf Club Champions League. The team was selected as the runner-up of the
latest edition of the Yemeni League. The association asked the club to participate to gain international experience for more Yemeni teams since the league winner,
Ahli Sanaa Club, entered the tournament in the
previous edition. The competition would mark the first time the club represented Yemen in international competition. In preparation for the tournament, the club imported several new recruits including Saudi manager Bandar Basarih and
Burundi international Chancel Ndaye, among other foreign and domestic players. which ended in a 2–0 victory for Al-Tadamun Al-Tadamun played its first ever competitive continental fixture, a loss 5–0 against
Al-Rayyan SC of
Qatar on 1 October 2025 to open the competition. In its next match, the Yemenis defeated
Al Shabab 2–0. With the victory, Al-Tadamun became the first Yemeni club to defeat a club from
Saudi Arabia in an official competition. After the first three matches of the tournament, the club had four points and sat second in Group B behind Al-Rayyan SC with a chance to qualify for the knockout stages. ==Stadium==