According to the
Synaxarion, Alexander was originally from
Calabria in Italy and his parents were called George and Vryaine. From a very young age, he was given to God and stayed in a
monastery, where he cultivated virtue and became a good labourer of God's commands. He was granted divine visions, while for twenty days he stayed completely
fasting. But he also stayed naked for four years and fell into thousands of problems because of attacks of the
Saracens. In this way, he lived many years traveling around Greece with his pupils Vitalius and Nicephorus. Alexander was elected as a
vicar to assist the aged bishop
Metrophanes of Byzantium. According to
Gelasius of Cyzicus, Metrophanes was alive during the
First Council of Nicaea (325), but could not partake due to his age and ill health, so he sent instead Alexander of Constantinople, whom he destined as his successor. Metrophanes was most likely already dead by then. Alexander succeeded him at the age of 73 in 314. During his episcopacy, Alexander engaged in debate with
pagan philosophers and opposed
heresies. He was highly praised by
Gregory Nazianzus and
Epiphanius of Salamis.
Theodoret called him an "apostolic" bishop. Alexander served as bishop for about 23 years, during which time he distinguished himself by his virtues and administrative abilities. == Arian controversy ==