Two substances from
Aloe vera – a clear
gel and its yellow
latex – are used to manufacture commercial products. There is conflicting evidence regarding whether
Aloe vera is effective as a treatment for wounds or burns. On the other hand,
Aloe vera compared favorably to
silver sulfadiazine in treating second- and third-degree burns in a 2022 meta-analysis, and a 2023 review found it an effective basis for medical
hydrogels.
Aloe vera gel is used commercially as an ingredient in
yogurts, beverages, and some desserts, Use of topical aloe vera in small amounts is likely to be safe.
Aloe vera and its (alcohol) extracts have potential toxicity, with
side effects occurring at some dose levels both when ingested and when applied topically. Chronic ingestion of aloe (dose of 1 gram per day) cause adverse effects, including
hematuria, weight loss, and cardiac or kidney disorders. The extracts and quantities typically used for such purposes are associated with toxicity in a dose-dependent way.
Commodities Aloe vera is used on
facial tissues where it is promoted as a moisturizer and anti-irritant to reduce chafing of the nose. Cosmetic companies commonly add sap or other derivatives from
Aloe vera to products such as makeup, tissues, moisturizers, soaps, sunscreens, incense, shaving cream, or shampoos. A review of academic literature notes that its inclusion in many hygiene products is due to its "moisturizing emollient effect". The cosmetic industry limits the anthraquinone content of aloe extracts to 50 ppm. ==Toxicity==