Cincinnati Bengals Whitworth was selected by the
Cincinnati Bengals in the second round (55th overall) in the
2006 NFL draft. He made his NFL debut on special teams on September 10 against Kansas City. He started at left guard in the following week against the
Cleveland Browns, as part of a line shuffle where left guard
Eric Steinbach replaced injured
Levi Jones at left tackle. Whitworth helped the Bengals pile up 481 yards against Browns, including 145 rushing yards by
Rudi Johnson. He was in the starting lineup for
Carson Palmer. He also had a key block on Rudi Johnson's seven-yard touchdown run in first quarter. On July 25, 2008, Whitworth agreed in principle to a four-year extension worth a reported $30 million that would keep him in
Cincinnati through 2013. He was ejected from a regular season game against the Jacksonville Jaguars after getting into a fight with Jaguars defensive end
John Henderson. In 2009, head coach decided to move Whitworth from guard to left tackle and saw immediate impact. He started all sixteen games of the season, allowing just five sacks and helping running back
Cedric Benson have a breakout year rushing for 1,251 yards. On December 12, 2010, Whitworth caught a one-yard touchdown pass from
Carson Palmer against the
Pittsburgh Steelers. It was the first of his career, and he was the first Bengals offensive lineman to catch a touchdown pass since 1995. He was ejected from a game against the Oakland Raiders after throwing a punch during a skirmish late in the game. He was subsequently fined $26,260 for the incident. In January 2013, for the first time in his career, Whitworth was named a left tackle on the AFC Pro Bowl team. During the 2014 season, Whitworth allowed zero sacks and only one hit on quarterback
Andy Dalton. Due to his success, many pundits and experts have claimed that Whitworth was snubbed out of a second Pro Bowl berth, however, he was named second-team AP NFL All-Pro. He was voted as the 67th best player by his peers in the
2016 list. Whitworth signed a one-year contract extension with the Bengals on September 26, 2015.
Los Angeles Rams On March 9, 2017, Whitworth signed a three-year contract with the
Los Angeles Rams. In his first season with the Rams, Whitworth made it to his fourth Pro Bowl. He was ranked 87th by his peers on the
NFL Top 100 Players of 2018. In 2018, Whitworth helped the Rams reach
Super Bowl LIII after they defeated the
Dallas Cowboys in the Divisional Round and
New Orleans Saints in the
NFC Championship Game. The Rams lost to the
New England Patriots 13–3 in the Super Bowl. In the eighth week of the 2019 season, the Rams defeated the Bengals 24–10, giving Whitworth a victory over his former team. With that victory, Whitworth became only the 12th starter in league history to earn victories against all 32 NFL teams. On April 1, 2020, Whitworth signed a three-year contract with the Rams. On November 16, Whitworth was placed on injured reserve, as he was carted off the field after suffering a torn MCL and damaged PCL in a 23–16 home win over the
Seattle Seahawks in Week 10. He was placed on injured reserve the next day. He was activated on January 7, 2021, before the team's playoff game. Whitworth was named the 2021
Walter Payton NFL Man of the Year at the
11th Annual NFL Honors. Whitworth won his first Super Bowl in what would ultimately be his final game, after the Rams defeated his former team, the
Cincinnati Bengals, 23–20 in
Super Bowl LVI. On March 15, 2022, Whitworth announced his retirement after 16 seasons. ==NFL records==