As a result of her doctorate, she was awarded a
National Institutes of Health sponsored, 1-year post-doctoral training fellowship, at
Clark University and the
Worcester Foundation for Experimental Biology in
Shrewsbury, Massachusetts. She researched at Worcester Foundation between 1962 In 1979, she moved to Maryland, encouraged by
Cornelia Channing to join the
University of Maryland School of Medicine, first as an associate professor. and proved to be a significant improvement on
tamoxifen, the standard cancer drug used to treat
oestrogen receptor-positive breast cancer in postmenopausal women. The drug was first marketed in 1994. In 2005, Brodie received the prestigious
Kettering Prize, the first woman to receive the award, though she did not know she had been nominated. At the time, she was on the editorial board of multiple professional journals, reviewed grant applications for the NIH, had published over 200 papers in peer-reviewed journals, and was a member of the integration for the US Army Department of Defense Army Breast Cancer Program. In 2016, she retired from the University of Maryland. ==Personal life and death==