; : (Japanese) :Ami Matsuzaki (松崎 亜美), the protagonist of the anime, is a preschool student who is quite mature for her age and has just moved into a new home and neighborhood with her family. She is intelligent and imaginative, but grounded and a bit easily flustered. The revelation that a gate to Ani-Yoko is in her room, and the increasingly bizarre actions of her three visitors, frequently drive her to the brink of total distraction, yet she seems to have gotten used to their presence, with Ami sharing some of her regular life with them. Her date of birth is 15 December and her zodiac sign is
Sagittarius. ;Iyo : (Japanese) :Iyo (イヨ) is one of the three creatures from
AniYoko, known as "the Happy AniYoko Trio", who frequently visit Ami through the door on her floor. She looks like a stuffed rabbit, and can use a sort of energy discharged through the space between her ears for all kinds of effects. She can also store objects and liquids in her ears, to be dispensed as needed. Although she always tries to act cheerful and cute, she is frequently selfish and vain. She also has the habit of dying when abused or neglected, only to return to life when a suitable apology is made. She somewhat resembles a Snowshoe Rabbit. Her date of birth is 4 January and her zodiac sign is
Capricorn. ;Kenta : (Japanese) :Kenta (ケンタ) has the appearance of a stuffed bear. He is brusque, frequently rude, and sometimes picks up odd obsessions. He has a love-hate dynamic with Iyo, with whom he is always arguing or fighting but he still appears to be close to her. His attempts to assert his species' identity frequently end in disaster. He is always seen wearing a red scarf, and it is usually a sign that something is very wrong if he is without it. He also often gives the
punchline in jokes where all three of the trio are involved. Kenta was very close to an old human lady, whom he called grandmother (baa-chan) she moved away to live with her daughter and gave him his scarf as a farewell gift. He has a major crush on Ami's friend, Ku-Chan. His date of birth is 6 May and his zodiac sign is
Taurus. ;Issa : (Japanese) :Issa (イッサ) is a creature that looks like a stuffed panda. He refers to himself as "the
empathic one" of the trio, puts the most effort into trying to be nice to Ami, and makes many unsuccessful efforts to make peace between Iyo and Kenta. His date of birth is 23 November and his zodiac sign is Sagittarius. ;Mr. Yamanami : (Japanese) :Mr. Yamanami (ヤマナミさん Yamanami-san) is a horse, apparently the leader of AniYoko. He frequently appears to make a small contribution to the scene or some demand on the cast, and then departs. Issa has said that all the creatures of AniYoko must obey "Commander Yamanami" or face an unspecified but terrible punishment. Yamanami also operates a "black-market mail-order" service, which occasionally delivers goods to Ami's room. It is implied that there are numerous Yamanamis, occupying different roles in AniYoko society. His birthday and zodiac sign are unknown. ;Ayako Matsuzaki :Ayako is Ami's mother. She is occasionally heard, but she has never made a physical appearance. There is no indication that Ayako is aware of the existence of AniYoko or any of the strange events surrounding Ami's life, although she sometimes notices the effects when something Ami or the three creatures do affects their real-world activities. ;Kumiko Takeda : (Japanese) :Kumiko Takeda (竹田 久美子) is Ami's close friend. She is a rather timid and frail girl and is one of the few people who can see the AniYoko Trio and others as they really are (although she annoyingly looks for Kenta's batteries believing that he's a toy), and shares in some of the adventures that Ami has. She seems to be very open to what happens. Her date of birth is 21 May. Kenta appears to have a crush on her, much to Iyo's annoyance. Ku-chan suffers from a
paralyzing fear of horses due to an unfortunate incident in a stable (in anime, a horse bit her head when she was a baby), so any interaction she has with Yananami-san is extremely traumatic. Her date of birth is 21 May and her zodiac sign is
Gemini. ;Catherine Maekawa :Catherine Maekawa (カトリーヌ前川) is Ami's favorite
manga artist. It is revealed in the anime that she is currently engaged in a
manga series about
sumo wrestling. Iyo has been to her house, after stowing away in a fan letter written by Ami, but she did not appear to notice. ;Others: • Match & Pitch (まっち&ピッチ). and Naoko Suzuki :Match (まっち, Machi) is one of the recurring characters who appears sporadically. Match is originally a girl (which was confirmed with the dress she is wearing at the first ending theme of the anime), but in the Cartoon Network English dubbing, Match is addressed as a "he" throughout the entire series. She and Kenta go way back in the past as training partners in a Martial Arts Dojo and addresses him as
"Anikki" (Big Bro or Bro in Japanese). According to Yamanami-san, Match is also a Jack-of-all-Trades in the professional world and considers her as the greatest bane of the Yamanami Industries. It was never mentioned or confirmed what kind of animal Match is (in one episode in the anime, Kenta does not know himself), but she is rumored to be a
Tarsier. Her date of birth is 4 April and her zodiac sign is
Aries. Pitch (ピッチ, Pichi) is a Yellow Canary who accompanies Match to everywhere she goes. Pitch also serves as Match's assistant at work and does domestic duties for her. • Shima Shimako (しま シマ子). (Japanese) :Shima Shimako like Yamanami-san is also a Zebra who walks upright on two legs. She is Aniyoko's showbiz idol (Model, Actress, Singer/Dancer) and is admired by every girl in Ani-yoko. Being Ani-yoko's biggest celebrity, she has a bratty celebrity-attitude. Mr. Yamanami is very much obsessed with her and will do anything (to the point of closing out his business) just to get a date with her. She tries to "fix" bad fashions that she sees people make, but she makes it worse. ==Media==