Acting Cusack starred in her first film role in 1992, when she was cast in
A League of Their Own, as
Shirley Baker. She was in the 1996 comedy
Multiplicity, which starred
Michael Keaton and
Andie MacDowell. Also in 1996, she replaced
Anita Barone on
The Jeff Foxworthy Show until the series ended. In 1998, Cusack starred in
Maggie on
Lifetime Television. Cusack has made guest appearances in ''
Grey's Anatomy, Scandal, One Tree Hill, Charmed, Ghost Whisperer, The Unit, Boston Legal, Bones, Frasier, Ally McBeal, Criminal Minds, Private Practice, and Castle among others. In 2002, she guest-starred in the episode of Star Trek: Enterprise entitled "Carbon Creek". She had a small role in Grosse Pointe Blank, which starred her siblings John and Joan; appeared in the movie Accepted,
in which she plays Diane Gaines, mother to the lead character played by Justin Long; and appeared in the film What Planet Are You From?. She also co-starred in Ace Ventura Jr: Pet Detective'' as Melissa Robinson Ventura, the titular character's mother (replacing
Courteney Cox from the
original film). She also appeared in the SciFi series
Lost Room as Helen Ruber (two episodes, 2006). In 2015, she appeared in the first episode of
Fargo's second season. In 2016, she played Donna Dent in the
Clint Eastwood-directed Warner Bros. film
Sully, about Chesley Sullenberger and the events of Flight 1549, starring
Tom Hanks. She also made her first appearance as
Rebecca Bois, Chuck's ex wife, in season two of
Better Call Saul, later returning in season three.
Music In August 2021, Cusack formed the musical group "Ann Cusack and the Generation Jones Band" in which she is the lead singer. == Filmography ==