After graduating, Wojcicki worked as a healthcare consultant at Passport Capital, a San Francisco-based investment fund, she decided to forgo taking the
MCAT to enroll in medical school and instead decided to focus on biological research. Consumers could purchase testing kits that provided information on ancestry, health, and genetic traits. The company took saliva samples that were mailed in by buyers, and processed the genetic data, posting the results online for the buyer to view. The company was named for the 23 pairs of chromosomes in a normal human cell. The company's genome test kit was named "Invention of the Year" by
Time magazine in 2008. Beginning in 2015, the
Food and Drug Administration started to give approval to 23andMe's health-related tests, including risk from
cystic fibrosis,
sickle cell anemia, certain
cancers,
Alzheimer's,
Parkinson's, and
coeliac disease. In 2018, 23andMe entered into a four-year collaboration with
GlaxoSmithKline to develop new medicines. When Wojcicki took 23andMe
public through a merger with a
special-purpose acquisition company in 2021,
Forbes dubbed her the "newest self-made billionaire." By 2024, the company's valuation had fallen to two percent of its peak value of $6 billion, prompting Wojcicki to make a buyout offer to take the company private; the company's board of directors rejected her proposal and all seven independent directors quit. On March 24, 2025, it was reported that 23andMe had filed for Chapter 11 bankruptcy and Wojcicki had resigned as CEO effective immediately but would remain on the company’s board. On June 13, 2025, TTAM Research Institute, a non-profit led by Wojcicki, regained control of 23andMe through a $305 million deal, buying back nearly all of the company's assets.
Other business activities Wojcicki is a member of the Xconomists, an ad hoc team of editorial advisors for the tech news and media company
Xconomy. In October 2013,
Fast Company dubbed Wojcicki "The Most Daring CEO in America". She is a co-founder and board member of the
Breakthrough Prize. She was ranked 93rd in
Forbes's 2020 list of the
World's 100 Most Powerful Women. In August 2021 Wojcicki joined the board of
Cazoo. Wojcicki has been closely involved in the downtown business district of
Los Altos, California. In approximately 2005, Wojcicki and her then-husband Google co-founder
Sergey Brin bought at least half a dozen commercial properties in downtown Los Altos. Under the name of Passerelle Investment Company, they sponsored events and urban planning initiatives throughout the downtown business district. In 2016, the firm was renamed to Los Altos Community Investments and given a tighter focus on commercial real-estate development. In 2021, Los Altos Community Investments opened a food hall in downtown Los Altos called the State Street Market. The initiative expanded to include an arts-and crafts store, a video arcade, and an indoor play space. The focus of development was to create spaces that foster community interaction and enjoyment. ==Personal life==